Functional constipation

Functional constipation, known as chronic idiopathic constipation (CIC), is constipation that does not have a physical (anatomical) or physiological (hormonal or other body chemistry) cause. It may have a neurological, psychological or psychosomatic cause. A person with functional constipation may be healthy, yet has difficulty defecating. Chronic idiopathic constipation is similar to constipation-predominant irritable bowel syndrome (IBS-C); however, people with CIC do not have other symptoms of IBS, such as abdominal pain. Diagnosing CIC can be difficult as other syndromes must be ruled out as there is no physiological cause for CIC. Doctors will typically look for other symptoms, such as blood in stool, weight loss, low blood count, or other symptoms. To be considered functional constipation, symptoms must be present at least a fourth of the time. Possible causes are: Anismus Descending perineum syndrome Other inability or unwillingness to control the external anal sphincter, which normally is under voluntary control A poor diet An unwillingness to defecate Nervous reactions, including prolonged and/or chronic stress and anxiety, that close the internal anal sphincter, a muscle that is not under voluntary control Deeper psychosomatic disorders which sometimes affect digestion and the absorption of water in the colon There is also possibility of presentation with other comorbid symptoms such as headache, especially in children. Treatment options appear similar and include prucalopride, lubiprostone, linaclotide, tegaserod, velusetrag, elobixibat, bisacodyl, sodium picosulphate, and most recently, plecanatide. In children and adolescents with functional constipation, the first line treatment is polyethylene glycol; while other treatments such as increasing fiber or water intake above daily recommended levels or probiotics have not been found to be helpful. A 2014 meta-analysis of three small trials evaluating probiotics showed a slight improvement in management of chronic idiopathic constipation, but well-designed studies are necessary to know the true efficacy of probiotics in treating this condition.

À propos de ce résultat

Cette page est générée automatiquement et peut contenir des informations qui ne sont pas correctes, complètes, à jour ou pertinentes par rapport à votre recherche. Il en va de même pour toutes les autres pages de ce site. Veillez à vérifier les informations auprès des sources officielles de l'EPFL.

Concepts associés (2)

Séances de cours associées (2)

Biotechnologie alimentaire : innovations et impact sur la santé

Intéressez-vous aux innovations en biotechnologie alimentaire, y compris les suppléments de synbiotiques et les probiotiques dans le yogourt produit localement, en soulignant leurs avantages économiques et sanitaires.

Développement de médicaments contre la maladie de Parkinson

Explore les stratégies de développement de médicaments pour la maladie de Parkinson, y compris l'identification des cibles et les stratégies thérapeutiques potentielles.

Functional constipation

Syndrome de l'intestin irritable

Le syndrome de l'intestin irritable (appelé également troubles fonctionnels intestinaux, ou colopathie fonctionnelle, ou encore syndrome du côlon irritable) est une maladie chronique à symptomatologie digestive en rapport avec des modifications de la motricité et de la sensibilité de l'intestin intriquées avec des facteurs psychologiques. Le diagnostic nécessite d'éliminer les pathologies à expression similaire les plus communes. Sans gravité, cette maladie fréquente retentit sur la qualité de vie.