Publications de Kathryn Hess Bellwald

Shadows are bicategorical traces

Hochschild homology has proved to be an important invariant in algebra and homotopy theory, in particular due to its relevance in algebraic K-theory and fixed point theory, leading to the development of numerous variants of the original construction. Ponto ...

2025

Of mice and men: Dendritic architecture differentiates human from mouse neuronal networks

Henry Markram, Kathryn Hess Bellwald, Rodrigo de Campos Perin, Lida Kanari, Ying Shi, Julie Meystre, Alexis Arnaudon, Maurizio Ferdinando Pezzoli, Natali Barros Zulaica

The organizational principles that distinguish the human brain from other species have been a long-standing enigma in neuroscience. Focusing on the uniquely evolved human cortical layers 2 and 3, we computationally reconstruct the cortical architecture for ...

2025

Heterogeneous and higher-order cortical connectivity undergirds efficient, robust, and reliable neural codes

Kathryn Hess Bellwald, András Ecker, Daniela Egas Santander, Christoph Pokorny

To distinguish between subpopulations, we developed a metric based on the mathematical theory of simplicial complexes that captures the complexity of their connectivity by contrasting its higher-order structure to a random control and confirmed its relevan ...

2025

Modeling and Simulation of Neocortical Micro- and Mesocircuitry. Part I: Anatomy

Henry Markram, Kathryn Hess Bellwald, Eilif Benjamin Muller, Srikanth Ramaswamy, Michael Reimann, James Gonzalo King, Lida Kanari, Ying Shi, Armando Romani, Adrien Michel Achille Devresse

The function of the neocortex is fundamentally determined by its repeating microcircuit motif, but also by its rich, hierarchical, interregional structure with a highly specific laminar architecture. The last decade has seen the emergence of extensive new ...

2024

Reluctance Despite Recognition: Student Perceptions of Benefits of Group Work

Kathryn Hess Bellwald, Simone Deparis, Joelyn de Lima

As engineering educators pivot towards implementing evidence-based pedagogical strategies, group work - or collaborative work - is being increasingly used in undergraduate classrooms. In mathematics, collaboration is a crucial disciplinary practice. Partic ...

European Society for Engineering Education (SEFI)2024

Dynamics of CLIMP-63 S-acylation control ER morphology

Vassily Hatzimanikatis, Françoise Gisou van der Goot Grunberg, Graham Knott, Kathryn Hess Bellwald, Laurence Gouzi Abrami, Béatrice Kunz, Luciano Andres Abriata, Sylvia Ho, Catherine Maclachlan, Patrick Alain Sandoz

A key player in the formation of endoplasmic reticulum sheets is CLIMP-63, but mechanistic details remained elusive. Here authors combined cellular experiments and mathematical modelling to show that S-acylation of CLIMP-63 regulates its function by mediat ...

Nature Portfolio2023

Intact Drosophila central nervous system cellular quantitation reveals sexual dimorphism

Kathryn Hess Bellwald, Ying Shi, Evelyne Ruchti, Brian Donal McCabe, Soumya Banerjee, Samuel William Vernon, Wei Jiao, Gard Spreemann

Establishing with precision the quantity and identity of the cell types of the brain is a prerequisite for a detailed compendium of gene and protein expression in the central nervous system (CNS). Currently, however, strict quantitation of cell numbers has ...

eLIFE SCIENCES PUBL LTD2022

A Künneth theorem for configuration spaces

Kathryn Hess Bellwald

We construct a spectral sequence converging to the homology of the ordered configuration spaces of a product of parallelizable manifolds. To identify the second page of this spectral sequence, we introduce a version of the Boardman-Vogt tensor product for ...

2022

Computational synthesis of cortical dendritic morphologies

Henry Markram, Kathryn Hess Bellwald, Lida Kanari, Julian Charles Shillcock, Hugo Thabo Dictus, Werner Alfons Hilda Van Geit, Alexis Arnaudon, Benoît Jean-Albert Coste

Neuronal morphologies provide the foundation for the electrical behavior of neurons, the connectomes they form, and the dynamical properties of the brain. Comprehensive neuron models are essential for defining cell types, discerning their functional roles, ...

CELL PRESS2022

Preface

Kathryn Hess Bellwald

AMER INST MATHEMATICAL SCIENCES-AIMS2022