Horst VogelHorst Vogel est né en 1948 à Würzburg, Allemagne. Après ses études en chimie, il obtient le diplôme de chimie en 1974 de l'Université de Würzburg.Il entreprend ensuite un travail de doctorat au Max-Planck Institut für Biophysikalische Chemie de Göttingen, et obtient en 1978 le grade de docteur ès sciences de l'Université de Göttingen. De 1978 à 1983 il effectue des recherches au Max-Planck Institut für Biologie à Tübingen et en 1984, il rejoint le Biocentre à Bâle où il travaille jusqu'en 1989, effectuant une année au Karolinska Institute à Stockholm. En 1989, Horst Vogel rejoint l'institut de chimie physique de l'EPFL où il dirige un groupe travaillant dans les domaines de la biophysique et de la bioélectronique.
Depuis le 1er octobre 1994 il est profeseur en chimie physique des polymères et membranes au Département de chimie de EPFL. Ses intérêts de recherche sont l'étude de la structure et de la dynamique de récepteurs membranaires et l'auto-assemblage des biomolécules aux interfaces pour développer de nouveaux biocapteurs dans le domaine de micro- et nanotechnologie. Il enseigne les sciences du vivant, la biophysique et biochimie, et des chapitres concernant la biotechnologie.
Dipl. in Chemistry1974-Univ. Würzburg, DE
Ph.D.-1978-MPI für Biophys. Chemie, Göttingen, DE
Françoise Gisou van der Goot GrunbergGisou van der Goot est responsable du Laboratoire de Biologie Cellulaire et Membranaire et co-fondatrice de l'Institut dInfectiologie, à la Faculté des Sciences de la Vie de l'EPFL.Depuis 2021, Prof. van der Goot est Vice-présidente pour la transformation responsable, moteur du changement de l’EPFL vers une culture inclusive et un campus durable. De 2014 à 2020, Prof. van der Goot a occupé la fonction de Doyenne de cette même Faculté.Avant sa nomination à l'EPFL, en 2006, elle était Cheffe de Groupe à la Faculté des Sciences de lUniversité de Genève (UNIGE), puis Professeure Associée à la Faculté de Médecine. Prof. van der Goot a d'abord obtenu un diplôme dIngénieur de l'Ecole Centrale de Paris avant dentamer une thèse en Biophysique Moléculaire au CEA de Saclay (Université de Paris VI), suivie dun séjour postdoctoral au Laboratoire Européen de Biologie Moléculaire (EMBL) à Heidelberg (Allemagne). Différentes distinctions lui ont été décernées, dont, en 2001, le Prix Young Investigator de l'EMBO (Organisation européenne de Biologie Moléculaire), puis, en 2005, le soutien par le programme international du Howard Hughes Medical Institute (HHMI, Etats-Unis); en 2009, elle a été la première femme à obtenir le Prix Marcel Benoist. La même année, elle est élue membre de lEMBO. Les domaines dexpertise du Prof. van der Goot incluent les mécanismes moléculaires et cellulaires des toxines bactériennes, l'organisation des membranes (des mammifères) et la biologie des organelles. Prof. van der Goot est membre du conseil scientifique de diverses organisations telles que le Fonds National Suisse de la Recherche Scientifique (SNF), le Conseil Suisse de la Science et de la Technologie (CSST) et le Conseil Européen de la Recherche (ERC).
Jürgen BruggerI am a Professor of Microengineering and co-affiliated to Materials Science. Before joining EPFL I was at the MESA Research Institute of Nanotechnology at the University of Twente in the Netherlands, at the IBM Zurich Research Laboratory, and at the Hitachi Central Research Laboratory, in Tokyo, Japan. I received a Master in Physical-Electronics and a PhD degree from Neuchâtel University, Switzerland. Research in my laboratory focuses on various aspects of MEMS and Nanotechnology. My group contributes to the field at the fundamental level as well as in technological development, as demonstrated by the start-ups that spun off from the lab. In our research, key competences are in micro/nanofabrication, additive micro-manufacturing, new materials for MEMS, increasingly for wearable and biomedical applications. Together with my students and colleagues we published over 200 peer-refereed papers and I had the pleasure to supervise over 25 PhD students. Former students and postdocs have been successful in receiving awards and starting their own scientific careers. I am honoured for the appointment in 2016 as Fellow of the IEEE “For contributions to micro and nano manufacturing technology”. In 2017 my lab was awarded an ERC AdvG in the field of advanced micro-manufacturing.
Hilal Lashuel2012-2013 Visiting Professor, Standford University. Stanford School of Medicine
2011- Associate Professor of Life Sciences-Brain Mind Institute-EPFL
Dir. Laboratory of Chemical Biology of Neurodegeneration
2005-2011 Assistant Professor of Life Sciences-Brain Mind Institute-EPFL
Dir. Laboratory of Molecular Neurobiology and Neuroproteomics
2005-2008 Director- EPFL Proteomic Core Facility
2002-2004 Instructor of Neurology- Harvard Medical School and Brigham and Women's
Hospital
2001-2002 Sabbatical Fellow- Laboratory for Drug Discovery in Neurodegeneration
Harvard Medical School,
2001-2002 Post-doctoral Fellow- Center for Neurologic Diseases
Harvard Medical School and Brigham and Women's Hospital
Advisor- Prof. Peter T. Lansbury
2000-2001 Research Scientist, The Picower Institute for Medical Research, Great Neck
New York
1994-2000 PhD Student; Texas A&M University and the Scripps Research Institute
Advisor- Prof. Jeffery W. Kelly
1990-1994 B.S. City University of New York, Brooklyn College
Dr. Hilal A. Lashuel received his B.Sc. degree in chemistry from the City University of New York in 1994 and completed his doctoral studies at Texas A&M University and the Scripps Research Institute in 2000. After obtaining his doctoral degree, he became a research fellow at the Picower Institute for Medical Research in Long Island New York. In 2001, he moved to Harvard Medical School and the Brigham and Women's Hospital as a research fellow in the Center for Neurologic Diseases and was later promoted to an instructor in neurology at Harvard Medical School. During his tenure (2001-2004) at Harvard Medical School his work focused on understanding the mechanisms of protein misfolding and fibrillogenesis and the role of these processes in the pathogenesis of Parkinson's and Alzheimer's disease. In 2005 Dr. Lashuel moved Switzerland to join the Brain Mind Institute at the Swiss Federal Institute of Technology Lausanne as a tenure-track assistant professor in neurosciences. Currently, Dr. Lashuel is an associate professor of life sciences and the director of the laboratory of molecular and chemical biology of neurodegeneration. (http://lashuel-lab.epfl.ch/).
Research efforts in the Lashuels laboratory focus on understanding the molecular mechanisms of neurodegeneration and developing novel strategies to diagnose and treat neurodegenerative diseases such as Alzheimers and Parkinsons disease. Research in the Lashuel lab is funded by several international funding agencies and foundations, including the Swiss National Science Foundation, European FP7 program (Marie Curie and ERC grants), Human Science Frontiers, Strauss Foundation, Cure the Huntingtons disease foundation and Michael J Fox foundation and is supported by collaborations with pharmaceutical and biotech companies (http://lashuel-lab.epfl.ch/page-50538-en.html), Nestle, Merck-Serono, AC Immune and Johnson and Johnson.
Dr. Lashuels research has resulted in the characterization of novel quaternary structure intermediates on the amyloid pathway, identification of potential therapeutic targets, and new hypotheses concerning the mechanisms of pathogenesis in Alzheimers disease, Parkinsons disease and related disorders. Dr. Lashuel scientific contribution to this field includes i) more than100 publications in major peer reviewed journals including Nature journals, Cell, PNAS, JBC, J. Neuroscience JACS, and Angewandtie Chemie; ii) three patents on novel strategies for preventing protein aggregation and treating autoimmune and inflammatory diseases; iii) more than 150 invited lectures since 2002 and more than 5500 citations (7800 citation-Google Scholar) since 1996. Dr. Lashuel has received several pre-doctoral and post-doctoral awards and fellowships and was the recipient of two prestigious awards given to young investigators; Human Science Frontiers young investigator research award and the European Research Council (ERC) starting independent researcher grant and the ERC proof of concept award (2013) These awards provide more than $2.5 Million to Dr. Lashuel to translate some of his ideas and projects into novel strategies for diagnosing and treating neurodegenerative diseases such as Alzheimers and Parkinsons disease. Dr. Lashuel has chaired and co-organized several international conferences and serves as an academic editor for PLoS ONE, an associate editor for frontiers of molecular neuroscience, member of the Editorial advisory board of ChemBioChem and ad hoc reviewer for several international scientific journals and funding agencies. Stewart ColeProfessor Stewart Cole is an international authority in bacterial molecular-genetics and genomics. He has made outstanding contributions in several fields including: bacterial anaerobic electron transport; genome analysis of retroviruses and papillomaviruses; antibiotic resistance mechanisms; and the molecular microbiology of toxigenic clostridia. His studies on isoniazid and multidrug resistance in Mycobacterium tuberculosis, together with his pioneering work on the pathogenicity, evolution and genomics of the tubercle and leprosy bacilli, have made him an undisputed leader in the field of mycobacterial research. The findings of his research are of direct relevance to public health and disease-control in both the developing world and the industrialised nations. He has published over 250 scientific papers and review articles, and holds many patents.
Klaus KernKlaus Kern is Professor of Physics at EPFL and Director and Scientific Member at the Max-Planck-Institute for Solid State Research in Stuttgart, Germany. He also is Honorary Professor at the University of Konstanz, Germany. His present research interests are in nanoscale science, quantum technology and in microscopy at the atomic limits of space and time. He holds a chemistry degree and PhD from the University of Bonn and a honorary doctors degree from the University of Aalborg. After his doctoral studies he was staff scientist at the Research Center Jülich and visiting scientist at Bell Laboratories, Murray Hill before joining the Faculty of EPFL in 1991 and the Max-Planck-Society in 1998. Professor Kern has authored and coauthored close to 700 scientific publications, which have received nearly 60‘000 citations. He has served frequently on advisory committees to universities, professional societies and institutions and has received numerous scientific awards and honors, including the 2008 Gottfried-Wilhelm-Leibniz Prize and the 2016 Van‘t Hoff Prize. Prof. Kern has also educated a large number of leading scientists in nanoscale physics and chemistry. During the past twenty-five years he has supervised one hundred PhD students and sixty postdoctoral fellows. Today, more than fifty of his former students and postdocs hold prominent faculty positions at Universities around the world.
Giorgio MargaritondoDe nationalité américaine et suisse, Giorgio Margaritondo est né à Rome (Italie) en 1946. Il a reçu la Laurea cum laude en physique de l'Université de Rome en 1969. De 1969 à 1978, il a travaillé pour le Consiglio Nazionale delle Ricerche (CNR), à Rome, à Frascati et, pendant la période 1975-1977, chez Bell Laboratories aux Etats-Unis. De 1978 à 1990, il est professeur de physique à l'Université du Wisconsin, à Madison (Etats-Unis); en 1984, il est nommé vice-directeur au Centre de rayonnement synchrotron de la même université. En 1990, il est engagé à l'EPFL comme professeur ordinaire et dirige l'Institut de physique appliquée au Département de physique. Il a été également membre honoraire du corps professoral de l'Université Vanderbilt à Nashville. En 2001 il a été nommé doyen de la Faculté des sciences de base de l'EPFL; en 2004, il a été nommé Vice-président pour les affaires académiques.; en 2010 et jusqu'à sa retraite de l'EPFL en 2016 il est devenu Doyen de la formation continue. A côté de ses cours de physique générale, son activité de recherche porte sur la physique des semiconducteurs et des supraconducteurs (états électroniques, surfaces, interfaces) et des systèmes biologiques; ses principales méthodes expérimentales sont la spectroscopie et la spectromicroscopie électroniques, l'imagerie aux rayons x et la microscopie SNOM, y compris les expériences avec le rayonnement synchrotron et le laser à électrons libres. Auteur d'environ 700 articles scientifiques et de 9 livres, il a aussi été responsable de 1995 à 1998 des programmes scientifiques du Synchrotron ELETTRA à Trieste. Depuis 1997, il a été le coordinateur de la table ronde de la Commission européenne pour le rayonnement synchrotron, et président du conseil de la "Integrated Initiative" de la Commission européenne pour les synchrotrons et les lasers à électrons libres (IA-SFS, ensuite ELISA), le plus grand réseau au monde de laboratoires dans ce domaine. En 2011-2015, il a été Editor-in-Chief du Journal of Physics D (Applied Physics). A présent, il est vice-président du conseil de l'Università della Svizzera Italiana (USI) et président du Scientific and Technological Committee de l'Istituto Italiano di Tecnologia (IIT). Il est "Fellow" de l'American Physical Society et de l'American Vacuum Society; il est également "Fellow and Chartered Physicist" de l'Institute of Physics.
Johan AuwerxJohan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Philippe BuffatBorn in Lausanne (Switzerland) in 1942. EPUL physics engineer diploma in 1967 and EPFL PhD in physics in 1976. From 1966 he studies at the Experimental Physics Laboratory (Prof. J.P. Borel) the physical properties peculiar to the very small size metal crystals and gets a PhD degree for his thesis "Abaissement de la température de fusion de petits cristaux d'or par effet de taille thermodynamique" (Lowering of the melting temperature of small gold crystals by thermodynamic size effect). In 1971, he starts to develop an electron microscopy facility available to all EPFL students and researchers (nowadays Centre Interdisciplinaire de Microscopie Electronique CIME) that he manages till 2007. In parallel he teaches the principles of electron microscopy and the Experimental methods of physics at the Physics/Basic Sciences School (SB). In addition, he trains a large part of the facility users. Honorary professor BS/EPFL he carries-out a free-lance research at CIME and in collaboration with the Institute of Crystallography of the Russian Academy of Sciences (ICRAS, Moscow) and the International Centre of Electron Microscopy for Material Science (IC-EM AGH Krakow) This activity covers all the techniques related to transmission and scanning electron microscopy applied to materials science and solid-state physics. His interest is directed towards the structure of nanocrystals, their size effects and behavior under strong electron irradiation, the phase transitions in perovskites, the characterization of nanophases, multilayer and interface structures of crystalline materials and bioceramics. More recently a large research part has moved to understanding/pointing-out the adequacy between the limits of the instruments and their interpretation means in regard of their use in a multiusers facility with a large turnover and a wide range of materials/structures. He is past-president (2006-2007) of the Société Française des Microscopies (Sfµ), honorary member of the Sfµ and of the Swiss Society of Optics and Microscopy (SSOM).
Nicolas GrandjeanNicolas Grandjean received a PhD degree in physics from the University ofNice Sophia Antipolis in 1994 and shortly thereafter joined the French National Center for Scientific Research (CNRS) as a permanent staff member. In 2004, he was appointed tenure-track assistant professor at the École polytechnique fédérale de Lausanne (EPFL) where he created the Laboratory for advanced semiconductors for photonics and electronics. He was promoted to full professor in 2009. He was the director of the Institute of Condensed Matter Physics from 2012 to 2016 and then moved to the University of California at Santa Barbara where he spent 6 months as a visiting professor. Since 2018, he is the head of the School of Physics at the EPFL. He was awarded the Sandoz Family Foundation Grant for Academic Promotion, received the “Nakamura Lecturer” Award in 2010, the "Quantum Devices Award” at the 2017 Compound Semiconductor Week, and “2016 best teacher” award from the EPFL Physics School. His research interests are focused on the physics of nanostructures and III-V nitride semiconductor quantum photonics.
