Publications de Marinela Gjoni Boillat

Membrane nanotubes drawn by optical tweezers transmit electrical signals between mammalian cells over long distances

Horst Vogel, Marinela Gjoni Boillat, Pedro Pascoal, Davor Kosanic

Biological cells continuously change shape allowing essential functions such as cell motility, vesicle-mediated release/uptake of soluble and membrane components or nanotube-mediated cell–cell communications. Here we use single cell micromanipulation to in ...

Royal Society of Chemistry2010

Optical trapping and micromanipulation of biological objects in microfluidic channels

Marinela Gjoni Boillat

The main aim of this project was to develop novel concepts for miniaturization of bioanalytical techniques for investigating biomolecular interactions. We used optical tweezers to selectively address individual biological objects in microfluidic channels. ...

EPFL2007

Determining a receptor-ligand interaction useful in e.g. drug screening involves repetitive application of reversibly binding fluorescent ligands with fast association-dissociation kinetics

Horst Vogel, Rudolf Hovius, Jean-Manuel Segura, Marinela Gjoni Boillat, Christoph Schreiter

NOVELTY - Determining a receptor-ligand interaction involves repeatedly contacting a cell comprising a receptor, with a ligand, of the receptor in which the ligand has a fluorescence labeling group and binds reversibly to the receptor under conditions in w ...

2006

Synthesis of nanoscopic optical fibers using lipid membranes as templates

Horst Vogel, Rudolf Hovius, Kurt Schenk, Pierre Stadelmann, Jean-Manuel Segura, Marinela Gjoni Boillat, Gopakumar Gopalakrishnan, Dimitrios Stamou, Cédric Gaillard

High-aspect-ratio, monocryst. Cd chloride nanowires doped with fluorescent CdS nanoparticles were synthesized using planar lipid membranes as templates. Cd2+ ions bound to the lipid bilayers (a) are released at low pH to the nanometer-sized, interlamellar ...

Wiley-VCH Verlag GmbH2005

Reversible sequential-binding probe receptor-ligand interactions in single cells

Horst Vogel, Rudolf Hovius, Jean-Manuel Segura, Marinela Gjoni Boillat, Christoph Schreiter

With the reversible sequential (ReSeq) binding assay, we present a novel approach for the ultrasensitive profiling of receptor function in single living cells. This assay is based on the repetitive application of fluorescent ligands that have fast assocn.- ...

2005