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Etienne Meylan

Cette personne n’est plus à l’EPFL

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Publications associées (30)

Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth

Rolf Gruetter, Anders Meibom, Graham Knott, Bernard Lanz, Stéphane Laurent Escrig, Nadine Fournier, Mario Gaetano Lepore, Etienne Meylan, Louise Helene Soegaard Jensen, Caroline Anne-Lyse Contat

Glucose utilization increases in tumors, a metabolic process that is observed clinically by F-18-fluorodeoxyglucose positron emission tomography (F-18-FDG-PET). However, is increased glucose uptake important for tumor cells, and which transporters are impl ...

2020

CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors

Etienne Meylan, Fabien Franco

Depleting regulatory T cells (T-reg cells) to counteract immunosuppressive features of the tumor microenvironment (TME) is an attractive strategy for cancer treatment; however, autoimmunity due to systemic impairment of their suppressive function limits it ...

NATURE PUBLISHING GROUP2020

Tumor-Promoting Ly-6G(+) SiglecF(high) Cells Are Mature and Long-Lived Neutrophils

Etienne Meylan

Myeloid cells co-expressing the markers CD11b, Ly-6G, and SiglecF can be found in large numbers in murine lung adenocarcinomas and accelerate cancer growth by fostering tumor cell invasion, angiogenesis, and immunosuppression; however, some of these cells' ...

2020

Durable and controlled depletion of neutrophils in mice

Etienne Meylan, Julien Robert Rémi Faget, Gael Luis Boivin, Caroline Anne-Lyse Contat, Jessica Christine Vazquez, Justine Pascual, Pierre-Benoit Bernard Ancey, Aspasia Gkasti

Neutrophils are an essential part of the innate immune system. To study their importance, experimental studies often aim to deplete these cells, generally by injecting anti-Ly6G or anti-Gr1 antibodies. However, these approaches are only partially effective ...

Nature Research2020

Low dose photodynamic therapy promotes a cytotoxic immunological response in a murine model of malignant pleural mesothelioma

Etienne Meylan, Julien Robert Rémi Faget, Yan Hao, Carsten Hao Ye Chong, Aspasia Gkasti

WILEY2019

Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis

Etienne Meylan, Loïc Steiner, Yuan Liu, Gonçalo Rodrigues

The development of effective therapies against brain metastasis is currently hindered by limitations in our understanding of the molecular mechanisms driving it. Here we define the contributions of tumour-secreted exosomes to brain metastatic colonization ...

NATURE PUBLISHING GROUP2019

Snail mediates repression of the Dlk1-Dio3 locus in lung tumor-infiltrating immune cells

Nadine Fournier, Etienne Meylan, Svenja Johanna Groeneveld, Julien Robert Rémi Faget

The epithelial-mesenchymal transition-inducing transcription factor Snail contributes to tumor progression in different malignancies. In the present study, we used a transcriptomics approach to elucidate the mechanism of Snail-mediated tumor growth promoti ...

2018

Neutrophils and Snail orchestrate the establishment of a protumor microenvironment in lung adenocarcinoma

Nicolas Jean Philippe Guex, Nadine Fournier, Etienne Meylan, Miguel Garcia, Julien Robert Rémi Faget, Svenja Johanna Groeneveld, Alessandra Piersigilli, Inti Zlobec, Gael Luis Boivin, Ioannis Xenarios

AMER ASSOC CANCER RESEARCH2018

Cellular Composition and Contribution of Tertiary Lymphoid Structures to Tumor Immune Infiltration and Modulation by Radiation Therapy

Etienne Meylan, Julien Robert Rémi Faget, Gael Luis Boivin

2018

RANKL Signaling Sustains Primary Tumor Growth in Genetically Engineered Mouse Models of Lung Adenocarcinoma

Nadine Fournier, Etienne Meylan, Julien Robert Rémi Faget, Caroline Anne-Lyse Contat

INTRODUCTION: NSCLC is the leading cause of cancer mortality. Recent retrospective clinical analyses suggest that blocking the receptor activator of NF-κB (RANK) signaling pathway inhibits the growth of NSCLC and might represent a new treatment strategy. M ...

2018

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Cellular Composition and Contribution of Tertiary Lymphoid Structures to Tumor Immune Infiltration and Modulation by Radiation Therapy

Etienne Meylan, Julien Robert Rémi Faget, Gael Luis Boivin

2018

RANKL Signaling Sustains Primary Tumor Growth in Genetically Engineered Mouse Models of Lung Adenocarcinoma

Nadine Fournier, Etienne Meylan, Julien Robert Rémi Faget, Caroline Anne-Lyse Contat

2018

Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth

Rolf Gruetter, Anders Meibom, Graham Knott, Bernard Lanz, Stéphane Laurent Escrig, Nadine Fournier, Mario Gaetano Lepore, Etienne Meylan, Louise Helene Soegaard Jensen, Caroline Anne-Lyse Contat

2020

Low dose photodynamic therapy promotes a cytotoxic immunological response in a murine model of malignant pleural mesothelioma

Etienne Meylan, Julien Robert Rémi Faget, Yan Hao, Carsten Hao Ye Chong, Aspasia Gkasti

WILEY2019

Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis

Etienne Meylan, Loïc Steiner, Yuan Liu, Gonçalo Rodrigues

NATURE PUBLISHING GROUP2019

Neutrophils and Snail orchestrate the establishment of a protumor microenvironment in lung adenocarcinoma

AMER ASSOC CANCER RESEARCH2018