Personne
Deniz Aydin
Cette personne n’est plus à l’EPFL
Publications associées (5)
Characterization of Coenzyme Q Biosynthesis Proteins through Integrative Modeling at the Protein-Membrane Interface
Integral and peripheral membrane proteins account for one-third of the human proteome, and they are estimated to represent the target for over 50% of modern medicinal drugs. Despite their central role in medicine, the complex, heterogeneous and dynamic nat ...
EPFL2019An Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis
Matteo Dal Peraro, Deniz Aydin
The biosynthesis of coenzyme Q presents a paradigm for how cells surmount hydrophobic barriers in lipid biology. In eukaryotes, CoQ precursors-among nature's most hydrophobic molecules-must somehow be presented to a series of enzymes peripherally associate ...
CELL PRESS2019Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity
Matteo Dal Peraro, Deniz Aydin, Xiao Guo
The UbiB protein kinase-like (PKL) family is widespread, comprising one-quarter of microbial PKLs and five human homologs, yet its biochemical activities remain obscure. COQ8A (ADCK3) is a mammalian UbiB protein associated with ubiquinone (CoQ) biosynthesi ...
Cell Press20161.3 Octave Supercontinuum Generation in Highly Ge-doped Photonic Crystal Fiber
Camille Sophie Brès, Deniz Aydin, Thibault Emmanuel North
We present a flat, visible 1.3-octave supercontinuum generated in a GeO2-doped photonic crystal fiber owing to an overlap of the modulation instability and Raman gain regions resulting in efficient energy transfer to new frequency components ...
Optical Society of America2016RoboGen: Robot Generation through Artificial Evolution
Dario Floreano, Joshua Evan Auerbach, Ilya Loshchilov, Przemyslaw Mariusz Kornatowski, Andrea Maesani, Titus Cieslewski, Ludovic Daler, Grégoire Hilaire Marie Heitz, Deniz Aydin, Pradeep Ruben Fernando
Science instructors from a wide range of disciplines agree that hands-on laboratory components of courses are pedagogically necessary (Freedman, 1997). However, certain shortcomings of current laboratory exercises have been pointed out by several authors ( ...
The MIT Press2014