Publications de Vytautas Navikas

Nanopore-based scanning system and method

Aleksandra Radenovic, Georg Fantner, Vytautas Navikas, Samuel Mendes Leitão

Nanopore-based scanning system including a probe structure comprising a nanopore; suction means configured to draw an end of a (bio)molecule inside the nanopore and inside the probe structure, single or multiple times; and displacement means configured to ...

2023

Spatially multiplexed single-molecule translocations through a nanopore at controlled speeds

Aleksandra Radenovic, Georg Fantner, Barney Frederick Drake, Helena Miljkovic, Simon Finn Mayer, Sanjin Marion, Vytautas Navikas, Samuel Mendes Leitão

In current nanopore-based label-free single-molecule sensing technologies, stochastic processes influence the selection of translocating molecule, translocation rate and translocation velocity. As a result, single-molecule translocations are challenging to ...

2023

Engineering Optically Active Defects in Hexagonal Boron Nitride Using Focused Ion Beam and Water

Aleksandra Radenovic, Andras Kis, Georg Fantner, Evgenii Glushkov, Nathan Cyprien Arsène Ronceray, Ahmet Avsar, Vytautas Navikas, Michal Daniel Macha, Cheol Yeon Cheon, Aqeel Ahmed

Hexagonal boron nitride (hBN) has emerged as a promising material platform for nanophotonics and quantum sensing, hosting optically active defects with exceptional properties such as high brightness and large spectral tuning. However, precise control over ...

AMER CHEMICAL SOC2022

Experimental Combination of Super-Resolution Optical Fluctuation Imaging with Structured Illumination Microscopy for Large Fields-of-View

Aleksandra Radenovic, Suliana Manley, Vytautas Navikas, Adrien Charles-François Raymond Descloux, Kristin Stefanie Grussmayer, Dora Mahecic

All fluorescence super-resolution microscopy techniques present trade-offs between, for example, resolution, acquisition speed, and live-cell compatibility. Structured illumination microscopy (SIM) improves the resolution through successive imaging of the ...

AMER CHEMICAL SOC2021

Time-Resolved Scanning Ion Conductance Microscopy for Three-Dimensional Tracking of Nanoscale Cell Surface Dynamics

Aleksandra Radenovic, Georg Fantner, Daniel Constam, Alexandre Louis André Persat, Barney Frederick Drake, Adrian Pascal Nievergelt, Vytautas Navikas, Samuel Mendes Leitão, Xavier Jean-Yves Pierrat, Charlène Cécile Geneviève Brillard

Nanocharacterization plays a vital role in understanding the complex nanoscale organization of cells and organelles. Understanding cellular function requires high-resolution information about how the cellular structures evolve over time. A number of techni ...

AMER CHEMICAL SOC2021

Correlative 3D microscopy of single cells using super-resolution and scanning ion-conductance microscopy

Aleksandra Radenovic, Georg Fantner, Barney Frederick Drake, Vytautas Navikas, Adrien Charles-François Raymond Descloux, Samuel Mendes Leitão, Kristin Stefanie Grussmayer

High-resolution live-cell imaging is necessary to study complex biological phenomena. Modern fluorescence microscopy methods are increasingly combined with complementary, label-free techniques to put the fluorescence information into the cellular context. ...

Nature Research2021

Bio-orthogonal Red and Far-Red Fluorogenic Probes for Wash-Free Live-Cell and Super-resolution Microscopy

Aleksandra Radenovic, Vytautas Navikas, Kristin Stefanie Grussmayer

Small-molecule fluorophores enable the observation of biomolecules in their native context with fluorescence microscopy. Specific labeling via bio-orthogonal tetrazine chemistry combines minimal label size with rapid labeling kinetics. At the same time, fl ...

2021

Biophysical applications of correlative scanning probe and super-resolution microscopy

Vytautas Navikas

Imaging live cells in their native environment is crucial for the understanding of complex biological phenomena. Modern optical microscopy methods such as fluorescence super-resolution microscopy are increasingly combined with complementary, label-free tec ...

EPFL2021

Direct Growth of Hexagonal Boron Nitride on Photonic Chips for High-Throughput Characterization

Aleksandra Radenovic, Martina Lihter, Evgenii Glushkov, Andrey Chernev, Vytautas Navikas, Reza Zamani, Jean Camille Benjamin Comtet

Adapting optical microscopy methods for nanoscale characterization of defects in two-dimensional (2D) materials is a vital step for photonic on-chip devices. To increase the analysis throughput, waveguide-based on-chip imaging platforms have been recently ...

AMER CHEMICAL SOC2021

Adaptive optics enables multimode 3D super-resolution microscopy via remote focusing

Aleksandra Radenovic, Sanjin Marion, Vytautas Navikas, Adrien Charles-François Raymond Descloux, Kristin Stefanie Grussmayer

A variety of modern super-resolution micro-scopy methods provide researchers with previouslyinconceivable biological sample imaging opportunities ata molecular resolution. All of these techniques excel atimaging samples that are close to the coverslip, how ...

2021