PGC-1alpha: turbocharging mitochondria

Johan Auwerx
2004
Article

Résumé

PGC-1alpha plays essential and diverse functions in the control of metabolism ranging from mitochondrial biogenesis and respiration to hepatic gluconeogenesis and muscle fiber-type switching. In a paper in this issue of Cell, the characterization of PGC-1alpha(-/-) mice illustrates these pleiotropic functions and reveals an unexpected role for PGC-1alpha in the brain.

Source officielle

https://infoscience.epfl.ch/record/135500?ln=fr

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PGC-1alpha: turbocharging mitochondria

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