Publication
Single-photon detector arrays for time-resolved fluorescence imaging
Publications associées (76)
Fluorescence lifetime imaging with a single-photon SPAD array using long overlapping gates: an experimental and theoretical study
Edoardo Charbon, Claudio Bruschini, Andrei Ardelean, Arin Can Ülkü
Developing large arrays of single-photon avalanche diodes (SPADs) with on-chip time-correlated single-photon counting (TCSPC) capabilities continues to be a difficult task due to stringent silicon real estate constraints, high data rates and system complex ...
2019Compact lensless digital holography
Microscopy is of high interest for biology since it allows imaging features that are too small to
be seen with naked eyes. However, cells are mostly transparent to visible and infrared light
which makes it difficult to see with a traditional microscope. To ...
EPFL2018Time-resolved Single-photon Detector Arrays for High Resolution Near-infrared Optical Tomography
Oxygenation is an important marker in many clinical settings, e.g. diagnosing ischaemic brain injuries in preterm infants or determining treatment effectiveness in cancer patients. Despite significant efforts to determine the oxygenation state of the human ...
EPFL2018Dynamic range extension for photon counting arrays
Edoardo Charbon, Claudio Bruschini, Ivan Michel Antolovic
Confocal microscopes use photomultiplier tubes and hybrid detectors due to their large dynamic range, which typically exceeds the one of single-photon avalanche diodes (SPADs). The latter, due to their photon counting operation, are usually limited to an o ...
2018Monolithic SPAD Arrays for High-Performance, Time-Resolved Single-Photon Imaging
Edoardo Charbon, Claudio Bruschini, Ivan Michel Antolovic, Samuel Burri, Arin Can Ülkü, Chunmin Zhang, Scott Anthony Lindner, Martin Wolf
SPAD (single-photon avalanche diode) arrays are single-photon sensors, which enable photon counting and unparalleled time-resolved imaging. In this paper, we will detail the architecture and characteristics of three representative SPAD arrays, implemented ...
IEEE2018A time-gated large-array SPAD camera for picosecond resolution real-time FLIM
Edoardo Charbon, Claudio Bruschini, Arin Can Ülkü
Single-photon avalanche diode (SPAD) arrays have recently emerged as promising detectors for many wide-field fluorescence lifetime imaging microscopy (FLIM) applications, thanks to their picosecond range temporal resolution, single-photon sensitivity and f ...
2018CMOS-Based Single-Photon Detectors: Technology and Applications
Edoardo Charbon, Claudio Bruschini, Myung Jae Lee
The goal of this paper is to introduce CMOS-based single-photon detectors in terms of technology and applications. We cover background and recent progress on the detectors and describe emerging applications based on the technology. ...
IEEE2018Widefield High Frame Rate Single-Photon SPAD Imagers for SPIM-FCS
Edoardo Charbon, Claudio Bruschini, Andrei Ardelean, Samuel Burri
Photon-counting sensors based on standard complementary metal-oxide-semiconductor single-photon avalanche diodes (SPADs) represent an emerging class of imagers that enable the counting and/or timing of single photons at zero readout noise (better than high ...
2018A CMOS SPAD Imager with Collision Detection and 128 Dynamically Reallocating TDCs for Single-Photon Counting and 3D Time-of-Flight Imaging
Edoardo Charbon, Ivan Michel Antolovic, Chunmin Zhang, Scott Anthony Lindner, Martin Wolf
Per-pixel time-to-digital converter (TDC) architectures have been exploited by single-photon avalanche diode (SPAD) sensors to achieve high photon throughput, but at the expense of fill factor, pixel pitch and readout efficiency. In contrast, TDC sharing a ...
2018LinoSPAD: a time-resolved 256x1 CMOS SPAD line sensor system featuring 64 FPGA-based TDC channels running at up to 8.5 giga-events per second
Edoardo Charbon, Claudio Bruschini, Harald Arjan Robert Homulle, Samuel Burri
LinoSPAD is a reconfigurable camera sensor with a 256x 1 CMOS SPAD (single-photon avalanche diode) pixel array connected to a low cost Xilinx Spartan 6 FPGA. The LinoSPAD sensor's line of pixels has a pitch of 24 pm and 40% fill factor. The FPGA implements ...
Spie-Int Soc Optical Engineering2016