Stimulation-induced increases of astrocytic oxidative metabolism in rats and humans investigated with 1-11C-acetate
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Microfluidic channels obtained by SU-8 photolithography and filled with liquid scintillators were recently demonstrated to be an interesting technology for the implementation of novel particle detectors. The main advantages of this approach are the intrins ...
Positron emission tomography (PET) and nuclear magnetic resonance spectroscopy (MRS) are two biomedical measurement techniques developed in the end of the XXth century, which drastically improved the amount of accessible information available in vivo. PET ...
n this paper we illustrate the core technologies at the basis of the European SPADnet project (www.spadnet.eu), and present the corresponding first results. SPADnet is aimed at a new generation of MRI-compatible, scalable large area image sensors, based on ...
The purpose of this study was to develop a two-compartment metabolic model of brain metabolism to assess oxidative metabolism from [1-C-11] acetate radiotracer experiments, using an approach previously applied in C-13 magnetic resonance spectroscopy (MRS), ...
Neural Metabolism In Vivo strives to offer a comprehensive and fundamental overview of cerebral metabolism by presenting leading-edge in vivo multimodal technology and its application in assessing neural activity, energy metabolism and neurotransmission in ...
Astrocytes have various important roles in brain physiology. To further elucidate the details of astrocytic functions under normal and pathological states, astrocyte-specific measurements are mandatory. For studying brain energy metabolism, the use of the ...
CF4 is used as a Cherenkov gas radiator in one of the Ring Imaging Cherenkov detectors at the LHCb experiment at the CERN Large Hadron Collider. CF4 is well known to have a high scintillation photon yield in the near and far VUV, UV and in the visible wave ...
Experimental evidence suggests that lactate is neuroprotective after acute brain injury; however, data in humans are lacking. We examined whether exogenous lactate supplementation improves cerebral energy metabolism in humans with traumatic brain injury (T ...
Cerebrospinal fluid (CSF) is a colourless liquid that fills the ventricular space and serves several functions like buoyancy, chemical stability and protection. CSF is produced within the ventricles and partly by the ependyma cells. Part of it seeps toward ...
Similar to analog silicon photomultipliers (SiPMs), digital SiPMs (dSiPMs) essentially consist of an array of single-photon avalanche photodiodes (SPADs). Instead of a passive quench resistor, however, an active quenching circuit is locally integrated with ...