Publication

Computational generation of the Purkinje network driven by clinical measurements: The case of pathological propagations

Publications associées (33)

Implementation of an epicardial implantable MEMS sensor for continuous and real-time postoperative assessment of left ventricular activity in adult minipigs over a short- and long-term period

The sensing of left ventricular (LV) activity is fundamental in the diagnosis and monitoring of cardiovascular health in high-risk patients after cardiac surgery to achieve better short- and long-term outcome. Conventional approaches rely on noninvasive me ...

Aip Publishing2024

Left cardiac vagotomy rapidly reduces contralateral cardiac vagal electrical activity in anesthetized Gottingen minipigs

Silvestro Micera, Ivo Strauss

Background: The impact of acute unilateral injury on spontaneous electrical activity in both vagus nerves at the heart level is poorly understood. We investigated the immediate neuroelectrical response after right or left cardiac vagal nerve transection (V ...

Clare2023

A comprehensive mathematical model for cardiac perfusion

Alfio Quarteroni, Francesco Regazzoni, Christian Vergara

The aim of this paper is to introduce a new mathematical model that simulates myocardial blood perfusion that accounts for multiscale and multiphysics features. Our model incorporates cardiac electrophysiology, active and passive mechanics, hemodynamics, v ...

Berlin2023

Interrelation between cardiac and brain small-vessel disease: a pilot quantitative PET and MRI study

Bénédicte Marie Maréchal, Ricardo Alberto Corredor Jerez

Background: Small-vessel disease (SVD) plays a crucial role in cardiac and brain ischemia, but little is known about potential interrelation between both. We retrospectively evaluated 370 patients, aiming at assessing the interrelation between cardiac and ...

London2023

Active force generation contributes to the complexity of spontaneous activity and to the response to stretch of murine cardiomyocyte cultures

Stéphanie Lacour

Cardiomyocyte cultures exhibit spontaneous electrical and contractile activity, as in a natural cardiac pacemaker. In such preparations, beat rate variability exhibits features similar to those of heart rate variability in vivo. Mechanical deformations and ...

WILEY2022

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Determination of left ventricular (LV) end-systolic elastance (E- es ) is of utmost importance for assessing the cardiac systolic function and hemodynamical state in humans. Yet, the clinical use of E- es is not established due to the invasive nature and h ...

FRONTIERS MEDIA SA2021

Design and modelling of a tubular dielectric elastomer actuator with constrained radial displacement as a cardiac assist device

Yves Perriard, Yoan René Cyrille Civet, Armando Matthieu Walter, Jonathan André Jean-Marie Chavanne

In this paper, we propose an improvement of a dielectric elastomer actuator (DEA) based augmented aorta. The actuator is a multi-layered tubular DEA subject to the internal pressure of the blood. When activated in synchronisation with the heart, the DEA su ...

IOP PUBLISHING LTD2021

Biomechanics of diastolic dysfunction: a one-dimensional computational modeling approach

Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia, Stamatia Zoi Pagoulatou

Diastolic dysfunction (DD) is a major component of heart failure with preserved ejection fraction (HFpEF). Accordingly. a profound understanding of the underlying biomechanical mechanisms involved in DD is needed to elucidate all aspects of HFpEF. In this ...

AMER PHYSIOLOGICAL SOC2020

Mapping Biological Current Densities With Ultrafast Acoustoelectric Imaging: Application to the Beating Rat Heart

Pierre-Marc Jean Marie Dansette

Ultrafast acoustoelectric imaging (UAI) is a novel method for the mapping of biological current densities, which may improve the diagnosis and monitoring of cardiac activation diseases such as arrhythmias. This paper evaluates the feasibility of performing ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2019

Cylindrical Dielectric Elastomer Actuator for Cardiac Assist Device

Jonathan André Jean-Marie Chavanne

This work has been triggered because of the need for a new way to relieve the heart. Current solutions are based on invasive systems. The main problem of such assistance is infectious risks. State of the art to define an alternative has allowed highlightin ...

EPFL2019

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