High throughput second harmonic imaging for label-free biological applications
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EPFL2023
Second harmonic generation microscopy is used to image interfaces or non-centrosymmetric structures and molecules. Two-photon fluorescence microscopy can image molecules within cells without using markers. Thus those technics have lead to advances in our u ...
Frequency doubling of an infrared laser radiation in non-linear optical crystals is a widely used technique to obtain light in the visible range. The second harmonic generation process is influenced by several well-known parameters. In this article we stud ...
Dielectric metasurfaces have shown prominent applications in nonlinear optics due to strong field enhancement and low dissipation losses at the nanoscale. Chalcogenide glasses are one of the promising materials for the observation of nonlinear effects due ...
We report a detailed investigation on the second harmonic generation (SHG) emission from single 150 nm diameter non-centrosymmetric gold nanoparticles. Polarization-resolved analysis together with scanning electron microscopy images shows that these nanost ...
In this article we compare the two-photon photoluminescence and second harmonic generation from single connected gold nanodimers. Analyzing the particle size-dependent nonlinear optical spectra and performing excitation polarization resolved measurements u ...
Embodiments of the subject invention relate to a method and apparatus for performing measurements using multiphoton or second harmonic generation (SHG) scattered radiation from a sample including a turbid (scattering) medium includes providing a beam of la ...