Cystite interstitielleLe syndrome de la vessie douloureuse ou la cystite interstitielle connue sous le nom de Interstitial cystitis pour IC, possède plusieurs références anglophones. C'est une maladie méconnue et souvent mal diagnostiquée qui touche la vessie, la région pelvienne et le méat urinaire. La paroi de la vessie est normalement recouverte d'une couche de protection qui fait écran entre l'urine et le tissu de la vessie. Avec l'IC, la paroi de protection de la vessie s'amincit.
Bladder sphincter dyssynergiaBladder sphincter dyssynergia (also known as detrusor sphincter dyssynergia (DSD) (the ICS standard terminology agreed 1998) and neurogenic detrusor overactivity (NDO)) is a consequence of a neurological pathology such as spinal injury or multiple sclerosis which disrupts central nervous system regulation of the micturition (urination) reflex resulting in dyscoordination of the detrusor muscles of the bladder and the male or female external urethral sphincter muscles.
PrééclampsieLa prééclampsie ou pré-éclampsie, également appelée toxémie gravidique, est une hypertension artérielle gravidique qui peut apparaître dans la deuxième moitié de la grossesse (après d'aménorrhée), associée à une protéinurie. Le terme de prééclampsie fait référence au fait qu'il s'agit d'une condition clinique qui, lorsqu'elle n'est pas prise en charge, peut évoluer vers l'éclampsie, une crise convulsive généralisée qui constitue une situation d'urgence vitale. La prééclampsie affecte de 2 à 8 % des grossesses, selon les pays et l'ethnie.
Adaptive design (medicine)In an adaptive design of a clinical trial, the parameters and conduct of the trial for a candidate drug or vaccine may be changed based on an interim analysis. Adaptive design typically involves advanced statistics to interpret a clinical trial endpoint. This is in contrast to traditional single-arm (i.e. non-randomized) clinical trials or randomized clinical trials (RCTs) that are static in their protocol and do not modify any parameters until the trial is completed.
Pre-hospital emergency medicinePre-hospital emergency medicine (abbreviated PHEM), also referred to as pre-hospital care, immediate care, or emergency medical services medicine (abbreviated EMS medicine), is a medical subspecialty which focuses on caring for seriously ill or injured patients before they reach hospital, and during emergency transfer to hospital or between hospitals. It may be practised by physicians from various backgrounds such as anaesthesiology, emergency medicine, intensive care medicine and acute medicine, after they have completed initial training in their base specialty.
Circulation (journal)Circulation (abrégé en Circulation) est une revue scientifique hebdomadaire à comité de lecture qui publie des articles dans le domaine des maladies cardio-vasculaires et de l'hématologie. Les articles de plus de douze mois de ce journal sont en libre accès. D'après le Journal Citation Reports, le facteur d'impact de ce journal était de 39.9 en 2022. Actuellement, la direction de publication est assurée par Joseph Loscalzo. Circulation Circulation: Arrhythmia and Electrophysiology Circulation: Heart Failure
Mid-level practitionerMid-level practitioners, also called non-physician practitioners, advanced practice providers, or commonly mid-levels are health care providers who assess, diagnose, and treat patients but do not have as extensive of an education as a physician. The scope of a mid-level practitioner varies greatly between countries and even between individual practitioners.
Post-anesthesia care unitA post-anesthesia care unit, often abbreviated PACU and sometimes referred to as post-anesthesia recovery or PAR, or simply Recovery, is a vital part of hospitals, ambulatory care centers, and other medical facilities. Patients who received general anesthesia, regional anesthesia, or local anesthesia are transferred from the operating room suites to the recovery area. The patients are monitored typically by anesthesiologists, certified registered nurse anesthetists, and other medical staff.
Monitoring in clinical trialsClinical monitoring is the oversight and administrative efforts that monitor a participant's health and efficacy of the treatment during a clinical trial. Both independent and government-run grant-funding agencies, such as the National Institutes of Health (NIH) and the World Health Organization (WHO), require data and safety monitoring protocols for Phase I and II clinical trials conforming to their standards. Safety monitoring of a clinical trial is conducted by an independent physician with relevant expertise.
Index bispectralBispectral index (BIS) is one of several technologies used to monitor depth of anesthesia. BIS monitors are used to supplement Guedel's classification system for determining depth of anesthesia. Titrating anesthetic agents to a specific bispectral index during general anesthesia in adults (and children over 1 year old) allows the anesthetist to adjust the amount of anesthetic agent to the needs of the patient, possibly resulting in a more rapid emergence from anesthesia.