A polymer optoelectronic interface restores light sensitivity in blind rat retinas
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Replacement strategies arise as promising approaches in case of inherited retinal dystrophies leading to blindness. A fully organic retinal prosthesis made of conjugated polymers layered onto a silk fibroin substrate is engineered. First, the biophysical a ...
Progressive degeneration of photoreceptors is one of the major causes of adult blindness in “industrialized” countries; as an example, Retinitis pigmentosa defines a set of monogenic hereditary retinal diseases, with a prevalence of 1:4000 worldwide, cause ...
The first observation that PBBTPD, a low bandgap, ambipolar conjugated donor-acceptor (DA) polymer based on benzobisthiadiazole (BBT), possesses an open-shell singlet ground state as well as a thermally accessible triplet state is described. Similarly, int ...
Purpose: Sight restoration is one of the new frontiers for prosthetic devices that enable the electrical stimulation of neurons. In particular, diseases that affect the retinal pigment epithelium and photoreceptors but preserve the inner retinal layers are ...
Purpose:In the past decade, retinal prostheses emerged as promising technology to restore a primitive, although clinically useful, form of vision. However, fighting blindness with retinal prostheses require challenges not yet achieved. From a clinical pers ...
Organic bioelectronics aims at the intimate integration between organic materials and biological tissues in order to obtain a targeted functional outcome. In the last decades, conductive polymers have been successfully employed to interface excitable cells ...
Poly(3,4-ethylenedioxythiophene)-poly(styrenesulphonate) (PEDOT:PSS) is the most used organic hole injecting or hole transporting material. The hole carrying matrix PEDOT is highly doped by the acidic dopant PSS. When coated onto a substrate, PEDOT: PSS ma ...
Organic molecules (i.e. carbon-based) have opened a new and rapidly-growing industrial field in the optoelectronic market bringing to this field a new dimension of thinness and flexibility. In this context, this thesis has focused on one particular buildin ...
Sight restoration is one of the new frontiers for prosthetic devices that enable the electrical stimulation of neurons. In particular, diseases that affect the retinal pigment epithelium and photoreceptors but preserve the inner retinal layers are preferen ...
Organic semiconductors have emerged in the past two decades as promising materials for many technological applications. Thanks to their unique optoelectronic properties, they represent an ideal system to mimic natural photoreceptor functioning. This simila ...
