Publication

Privacy in the Genomic Era

Publications associées (40)

An Introduction to MPEG-G: The First Open ISO/IEC Standard for the Compression and Exchange of Genomic Sequencing Data

The development and progress of high-throughput sequencing technologies have transformed the sequencing of DNA from a scientific research challenge to practice. With the release of the latest generation of sequencing machines, the cost of sequencing a whol ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2021

Parallel and Scalable Bioinformatics

Stuart Anthony Byma

The field of genomics is likely to become the largest producer of data as a consequence of the large-scale application of next-generation sequencing technology for biological research and personalized medical treatments. The raw sequence data produced by t ...

EPFL2020

Population Genomics of Mycobacterium leprae Reveals a New Genotype in Madagascar and the Comoros

Stewart Cole, Andrej Benjak, Charlotte Avanzi, Philippe Busso, Pushpendra Singh, Thyago Leal Calvo

Human settlement of Madagascar traces back to the beginning of the first millennium with the arrival of Austronesians from Southeast Asia, followed by migrations from Africa and the Middle East. Remains of these different cultural, genetic, and linguistic ...

2020

A Crowdsourced Gameplay for Whole-Genome Assembly via Short Reads

Next-generation sequencing has revolutionized the field of genomics by producing accurate, rapid and cost-effective genome analysis with the use of high throughput sequencing technologies. This has intensified the need for accurate and performance efficien ...

INT ASSOC ONLINE ENGINEERING2020

Privacy-Enhancing Technologies for Medical and Genomic Data: From Theory to Practice

Jean Louis Raisaro

The impressive technological advances in genomic analysis and the significant drop in the cost of genome sequencing are paving the way to a variety of revolutionary applications in modern healthcare. In particular, the increasing understanding of the human ...

EPFL2018

Simulating the Large-Scale Erosion of Genomic Privacy Over Time

Mathias Jacques Jean-Marc Humbert, Verena Wolf, Xiaoyu Shen

The dramatically decreasing costs of DNA sequencing have triggered more than a million humans to have their genotypes sequenced. Moreover, these individuals increasingly make their genomic data publicly available, thereby creating privacy threats for thems ...

IEEE COMPUTER SOC2018

GenoShare: Supporting Privacy-Informed Decisions for Sharing Exact Genomic Data

Jean-Pierre Hubaux, Mathias Jacques Jean-Marc Humbert, Carmela González Troncoso, Amalio Telenti, Jean Louis Raisaro

The academic community has proposed many solutions to address the privacy concerns associated with genomic-data sharing. However, practitioners have not adopted these solutions due to their impact on the data utility. To address this problem, we introduce ...

EPFL infoscience2018

SmarPer: Context-Aware and Automatic Runtime-Permissions for Mobile Devices

Jean-Pierre Hubaux, Kévin Clément Huguenin, Italo Ivan Dacosta Petrocelli, Mohammad Emtiyaz Khan, Joana Catarina Soares Machado, Katarzyna Lucja Olejnik

Permission systems are the main defense that mobile platforms, such as Android and iOS, offer to users to protect their private data from prying apps. However, due to the tension between usability and control, such systems have several limitations that oft ...

IEEE2017

Persona: A High-Performance Bioinformatics Framework

James Richard Larus, Edouard Bugnion, Christos Kozyrakis, Stuart Anthony Byma, Sam David Whitlock

Next-generation genome sequencing technology has reached a point at which it is becoming cost-effective to sequence all patients. Biobanks and researchers are faced with an oncoming deluge of genomic data, whose processing requires new and scalable bioinfo ...

2017

SQC: Secure Quality Control for Meta-Analysis of Genome-Wide Association Studies

Jean-Pierre Hubaux, Jacques Fellay, Zhicong Huang, Huang Lin

Motivation: Due to the limited power of small-scale genome-wide association studies (GWAS), researchers tend to collaborate and establish a larger consortium in order to perform large-scale GWAS. Genome-wide association meta-analysis (GWAMA) is a statistic ...

Oxford University Press2017

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