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Physical exercise rescues adult neurogenesis, synaptic plasticity and memory in down syndrome mice
Publications associées (48)
Real world multimodal assessment of physical behavior change in health and disease
Sedentary lifestyle is currently considered a global pandemic, associated with major health problems such as cardiovascular disease and premature death. Regular physical activity (PA) is one way to address this problem, as it brings a variety of health ben ...
EPFL2023Sharpening the blades of the dentate gyrus: how adult-born neurons differentially modulate diverse aspects of hippocampal learning and memory
For decades, the mammalian hippocampus has been the focus of cellular, anatomical, behavioral, and computational studies aimed at understanding the fundamental mechanisms underlying cognition. Long recognized as the brain's seat for learning and memory, a ...
WILEY2023Principles of Network Plasticity in Neocortical Microcircuits
Synaptic plasticity underlies our ability to learn and adapt to the constantly changing environment. The phenomenon of synapses changing their efficacy in an activity-dependent manner is often studied in small groups of neurons in vitro or indirectly throu ...
EPFL20233D Pose Based Feedback For Physical Exercises
Pascal Fua, Mathieu Salzmann, Isinsu Katircioglu, Sena Kiciroglu, Ziqi Zhao, Hugues François Rémi Vinzant, Yuan Cheng, Ziyi Zhao
Unsupervised self-rehabilitation exercises and physical training can cause serious injuries if performed incorrectly. We introduce a learning-based framework that identifies the mistakes made by a user and proposes corrective measures for easier and safer ...
Springer2022Activities, Housing Situation and Other Factors Influencing Psychological Strain Experienced During the First COVID-19 Lockdown in Switzerland
Claudia Rebeca Binder Signer, Anna Pagani, Garance Clément, Livia Bianca Fritz, Ralph Hansmann
Background: The Coronavirus disease 2019 (COVID-19) crisis and the corresponding first nationwide lockdown from mid-March to 10 May 2020 engendered considerable psychological strain among people in Switzerland. This study analyzes determinants of changes i ...
2021Wearable multifunctional sweat-sensing system for efficient healthcare monitoring
Giovanni De Micheli, Sandro Carrara, Mandresy Ivan Ny Hanitra, Irene Taurino, Francesca Criscuolo, Nicolò Oliva, Simone Aiassa
Despite the huge expansion in recent years of sweat sensing and wearable technologies, several challenges are still open, including poor sample collection, separate sampling and analysis, low multi-sensing capabilities and materials toxicity. In this work, ...
2020Data-driven integration of hippocampal CA1 synaptic physiology in silico
Eilif Benjamin Muller, Srikanth Ramaswamy, Michael Reimann, Armando Romani, András Ecker, Michele Migliore, Szabolcs Kali, Sàra Sàray, Audrey Mercer
The anatomy and physiology of monosynaptic connections in rodent hippocampal CA1 have been extensively studied in recent decades. Yet, the resulting knowledge remains disparate and difficult to reconcile. Here, we present a data-driven approach to integrat ...
2020Impact of aerobic exercise type on blood flow, muscle energy metabolism, and mitochondrial biogenesis in experimental lower extremity artery disease
Rolf Gruetter, Carole Poitry-Yamate
Exercise training (ET) is recommended for lower extremity artery disease (LEAD) management. However, there is still little information on the hemodynamic and metabolic adaptations by skeletal muscle with ET. We examined whether hindlimb perfusion/vasculari ...
2020Wearable multi-electrode platform for ion sensing
With the growth of personalized medicine and e-Health, there has been an increasing interest in the development of accurate sensing systems able to support this healthcare revolution for both in- and off-hospital monitoring. Remote biosensing devices can d ...
EPFL2020PREC 2019: Personal Robots for Exercising and Coaching
Exercising is strongly recommended for prevention and treatment of pathologies with high prevalence such as cardiovascular diseases, cancer, and diabetes. The World Health Organization (WHO) states that insufficient physical activity is one of the leading ...
IEEE2019