Method for quantitative measurement of a biomarker by in situ immunofluorescence and uses thereof
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The present invention relates to a method for the manufacture of a peptidic folding precursor (Switch-Peptide) stable and soluble at physiological conditions, derived from a peptide having a potential for self-assembling and fibrillogenesis. Another object ...
Crohn's disease is an inflammatory bowel disease originating from an overwhelming response of the mucosal immune system. Low dose photodynamic therapy (PDT) may modify the mucosal immune response and thus serve as a therapy for Crohn's disease. Most patien ...
Using strong-disorder renormalization group, numerical exact diagonalization, and quantum Monte Carlo methods, we revisit the random antiferromagnetic XXZ spin-1/2 chain focusing on the long-length and ground-state behavior of the average time-independent ...
The present invention relates to novel organometallic compds. for use as a medicine, in particular in photodynamic therapy against various diseases, such as cancer. The compds. comprise a central porphyrin or phthalocyanine backbone to which ligand linkers ...
Provided herein are methods and compositions for treating or preventing metabolic disorders, such as obesity and diabetes. Methods may comprise modulating the activity or level of a sirtuin, such as SIRT1 or Sir2. Exemplary methods comprise contacting a ce ...
The invention discloses a method for the manuf. of a peptidic folding precursor (switch-peptide) stable and sol. at physiol. conditions, derived from a peptide having a potential for self-assembling and fibrillogenesis. Another object of the invention is t ...
The need for better drugs to treat tuberculosis has never been greater. Despite insufficient funding for discovery research, intensive efforts have been made to find and develop new lead compounds capable of reducing the duration of the present treatment k ...
The present invention relates to nanoparticles having a mean diameter of < 500nm and comprising, at their surface, a selected material. The nanoparticles are taken up by cells under physiological conditions and can be used to isolate interaction partners o ...
Availability of an ultra-short-course drug regimen capable of curing patients with tuberculosis in 2 to 3 mo would significantly improve global control efforts. Because immediate prospects for novel treatment-shortening drugs remain uncertain, we examined ...
The need for better drugs to treat tuberculosis has never been greater. Despite insufficient funding for discovery research, intensive efforts have been made to find and develop new lead compounds capable of reducing the duration of the present treatment k ...