Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitro
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Skeletal muscle composed of myofibers and a small amount of muscle stem cells (MuSCs). It plays important roles in energy metabolism. Some of the key metabolites, such as NAD+ and acetyl-CoA were recently found to regulate muscle and MuSCs function. Most o ...
The project deals with the finite element approximation of the monodomain equation, which models the propagation of the electrical potential in the cardiac muscle through a coupled system of PDE’s. The goal is to recover the shape of an infarcted area insi ...
Background: Hypospadias and urethral strictures are conditions requiring additional tissue for reconstruction. Due to a limited source of tissue, autologous skin and oral mucosa are frequently used. However, long-term follow-up studies demonstrated signifi ...
Skeletal muscle exhibits a high plasticity and accordingly can quickly adapt to different physiological and pathological stimuli by changing its phenotype largely through diverse epigenetic mechanisms. The nuclear receptor corepressor 1 (NCoR1) has the abi ...
The aim of this paper is to propose a muscle control method for a humanoid musculoskeletal arm that mimics human muscle coordination from an engineering viewpoint. As muscle control is posed as a redundancy problem, the resulting muscle force corresponds t ...
Inst Control Robotics & Systems, Korean Inst Electrical Engineers2015
Cardiac and skeletal muscle function relies on a continuous energy production via fatty acid metabolism and mitochondrial oxidation of pyruvate, with a fine balance between substrate delivery and utilization. Changes in metabolism are increasingly being im ...
During embryonic development, the paraxial mesoderm becomes segmented into somites, within which proliferative muscle progenitors and muscle fibers establish the skeletal musculature. Here, we demonstrate that a gene network previously implicated in somite ...
Resting skeletal muscle has a preference for the oxidation of lipids compared to carbohydrates and a shift towards carbohydrate oxidation is observed with increasing exercise. Lactate is not only an end product in skeletal muscle but also an important meta ...
In this study, we present a quantitative approach to construct effective 3D muscle tissues through shape optimization and load impedance matching with electrical and optical stimulation. We have constructed long, thin, fascicle-like skeletal muscle tissue ...
Optogenetics is an emerging new technology for controlling live cell function with light. Skeletal muscles are genetically coded to express light-sensitive proteins so that the cell's behavior may be altered by illuminating a targeted portion of the cell. ...