Publication

Reverse engineering the motor control system

Publications associées (99)

Functional imaging of rostrocaudal spinal activity during upper limb motor tasks

Dimitri Nestor Alice Van De Ville, Silvestro Micera, Elvira Pirondini, Nawal Noëlle Kinany, Roberto Martuzzi

The spinal cord is the main interface between the brain and the periphery. It notably plays a central role in motor control, as spinal motoneurons activate skeletal muscles involved in voluntary movements. Yet, the spinal mechanisms underlying human moveme ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2019

Functional imaging of rostrocaudal spinal activity during upper limb motor tasks

Dimitri Nestor Alice Van De Ville, Silvestro Micera, Elvira Pirondini, Nawal Noëlle Kinany, Roberto Martuzzi

2019

Chronotopic maps in human supplementary motor area

Wietske Van der Zwaag, Domenica Bueti

Time is a fundamental dimension of everyday experiences. We can unmistakably sense its passage and adjust our behavior accordingly. Despite its ubiquity, the neuronal mechanisms underlying the capacity to perceive time remains unclear. Here, in two experim ...

2019

Control theory in biology and medicine: Introduction to the special issue

Auke Ijspeert

From September-December 2017, the Mathematical Biosciences Institute at Ohio State University hosted a series of workshops on control theory in biology and medicine, including workshops on control and modulation of neuronal and motor systems, control of ce ...

SPRINGER2019

Experimentally induced limb-disownership in mixed reality

Oliver Alan Kannape, Bigna Lenggenhager

The seemingly stable construct of our bodily self depends on the continued, successful integration of multi sensory feedback about our body, rather than its purely physical composition. Accordingly, pathological disruption of such neural processing is link ...

PERGAMON-ELSEVIER SCIENCE LTD2019

Neural correlates of performance monitoring during discrete and continuous tasks

Michael Eric Anthony Pereira

Monitoring our actions is a key function of the brain for adaptive and successful behavior. Actions can be discrete such as when pressing a button, or continuous, such as driving a car. Moreover, we evaluate our actions as correct or erroneous (performance ...

EPFL2018

A Robotic System for Adaptive Training and Function Assessment of Forelimb Retraction in Mice

Silvestro Micera, Stefano Lai, Maria Pasquini, Sara Conti

Rodent models are decisive for translational research in healthy and pathological conditions of motor function thanks to specific similarities with humans. Here, we present an upgraded version of the M-Platform, a robotic device previously designed to trai ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2018

A Computational Approach for the Design of Epidural Electrical Spinal Cord Stimulation Strategies to Enable Locomotion after Spinal Cord Injury

Emanuele Formento

Spinal cord injury (SCI) is a major cause of paralysis with currently no effective treatment. Epidural electrical stimulation (EES) of the lumbar spinal cord has been shown to restore locomotion in animal models of SCI, but has not yet reached the same lev ...

EPFL2018

Imaging neural activity in the ventral nerve cord of behaving adult Drosophila

Michaël Unser, Pavan P Ramdya, Florian Aymanns, Denis Fortun, Chin-Lin Chen, Laura Joan Hermans

To understand neural circuits that control limbs, one must measure their activity during behavior. Until now this goal has been challenging, because limb premotor and motor circuits have been largely inaccessible for large-scale recordings in intact, movin ...

2018

Cortico–reticulo–spinal circuit reorganization enables functional recovery after severe spinal cord contusion

Grégoire Courtine, Bernard Schneider, Quentin Barraud, Léonie Asboth, Mark Andrew Anderson, Lucia Florinda Friedli Wittler, Laetitia Danielle Philippine Baud, Polina Shkorbatova, Janine Beauparlant, Galyna Pidpruzhnykova, Selin Anil, Julie Kreider, Cristina Martinez Gonzalez, Elodie Rey

Severe spinal cord contusions interrupt nearly all brain projections to lumbar circuits producing leg movement. Failure of these projections to reorganize leads to permanent paralysis. Here we modeled these injuries in rodents. A severe contusion abolished ...

2018

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