The 6.9-angstrom structure of GlpF: A basis for homology modeling of the glycerol channel from Escherichia coli
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Electron crystallography of membrane proteins determines the structure of membrane-reconstituted and two-dimensionally (2D) crystallized membrane proteins by low-dose imaging with the transmission electron microscope, and computer image processing. We have ...
We formulate and investigate a statistical inverse problem of a random tomographic nature, where a probability density function on R3 is to be recovered from observation of finitely many of its two-dimensional projections in random and unobserv ...
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Microporous limestones composed of micrite crystals constitute sizeable hydrocarbon reservoirs throughout the world and especially in the Middle East. However, the crystallization history of micrites is poorly understood. Scanning electronic microscopy (SE ...
Electron crystallography is a powerful technique for the structure determination of membrane proteins as well as soluble proteins. Sample preparation for 2D membrane protein crystals is a crucial step, as proteins have to be prepared for electron microscop ...
For the next generation of radio interferometric telescopes it is of paramount importance to incorporate wide field-of-view (WFOV) considerations in interferometric imaging, otherwise the fidelity of reconstructed images will suffer greatly. We extend comp ...
Gamma-secretase, an integral membrane protein complex, catalyzes the intramembrane cleavage of the beta-amyloid precursor protein (APP) during the neuronal production of the amyloid beta-peptide. As such, the protease has emerged as a key target for develo ...
The contractile tail of bacteriophage T4 is a molecular machine that facilitates very high viral infection efficiency. Its major component is a tail sheath, which contracts during infection to less than half of its initial length. The sheath consists of 13 ...
This paper brings together two fundamental topics: polyhedral projection and parametric linear programming. First, it is shown that, given a parametric linear program (PLP), a polyhedron exists whose projection provides the solution to the PLP. Second, the ...
The gating ring of cyclic nucleotide-modulated channels is proposed to be either a two-fold symmetric dimer of dinners or a four-fold symmetric tetramer based on high-resolution structure data of soluble cyclic nucleotide-binding domains and functional dat ...