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Disparate temperature-dependent virus-host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium
Publications associées (47)
The COUGHVID crowdsourcing dataset, a corpus for the study of large-scale cough analysis algorithms
David Atienza Alonso, Tomas Teijeiro Campo, Lara Orlandic
Cough audio signal classification has been successfully used to diagnose a variety of respiratory conditions, and there has been significant interest in leveraging Machine Learning (ML) to provide widespread COVID-19 screening. The COUGHVID dataset provide ...
2021The COUGHVID crowdsourcing dataset: A corpus for the study of large-scale cough analysis algorithms
David Atienza Alonso, Tomas Teijeiro Campo, Lara Orlandic
Cough audio signal classification has been successfully used to diagnose a variety of respiratory conditions, and there has been significant interest in leveraging Machine Learning (ML) to provide widespread COVID-19 screening. However, there is currently ...
2020Spin cascade and doming in ferric hemes: Femtosecond X-ray absorption and X-ray emission studies
Majed Chergui, Oliviero Cannelli, Christopher Alexander Arrell, Wojciech Gawelda, Giulia Fulvia Mancini, Frederico Alves Lima, Camila Bacellar Cases Da Silveira, Dominik Kinschel, Rebecca Ann Ingle, Jérémy Raymond Jean Maurice Rouxel, Samuel Menzi
The structure-function relationship is at the heart of biology, and major protein deformations are correlated to specific functions. For ferrous heme proteins, doming is associated with the respiratory function in hemoglobin and myoglobins. Cytochrome c (C ...
NATL ACAD SCIENCES2020Population Structure, Molecular Epidemiology, and beta-Lactamase Diversity among Stenotrophomonas maltophilia Isolates in the United States
Stenotrophomonas maltophilia is a Gram-negative, nonfermenting, environmental bacillus that is an important cause of nosocomial infections, primarily associated with the respiratory tract in the immunocompromised population. Aiming to understand the popula ...
2019Expanding beyond the natural protein repertoire to engineer targeted vaccines and diagnostics
Proteins have evolved over millions of years to carry out the vast majority of biological functions that are fundamental to life. Their three-dimensional structures and functions have been in the focus of biomedical research for many decades, and substanti ...
EPFL2019AltitudeOmics: Spontaneous Baroreflex Sensitivity During Acclimatization to 5,260 m: A Comparison of Methods
Jean-Marc Vesin, Sasan Yazdani
Introduction Baroreflex sensitivity (BRS) is essential to ensure rapid adjustment to variations in blood pressure (BP). Spontaneous baroreflex function can be assessed using continuous recordings of blood pressure. The goal of this study was to compare fou ...
FRONTIERS MEDIA SA2019FIBCD1 Binds Aspergillus fumigatus and Regulates Lung Epithelial Response to Cell Wall Components
Aspergillus fumigatus (A. fumigatus) is a ubiquitous fungus of clinical importance associated with development of various pulmonary diseases and allergic hypersensitivity reactions. It is protected against environmental stress by a cell wall that contains ...
FRONTIERS MEDIA SA2018Severe viral respiratory infections in children with IFIH1 loss-of-function mutations
Jacques Fellay, Amalio Telenti, Istvan Bartha, Christian Hammer, Thomas Junier, Samira Asgari
Viral respiratory infections are usually mild and self-limiting; still they exceptionally result in life-threatening infections in previously healthy children. To investigate a potential genetic cause, we recruited 120 previously healthy children requiring ...
Natl Acad Sciences2017Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota
Eva Sabrina Gollwitzer, Nicola Harris, Benjamin John Marsland
BACKGROUND: Helminth parasites have been reported to have beneficial immunomodulatory effects in patients with allergic and autoimmune conditions and detrimental consequences in patients with tuberculosis and some viral infections. Their role in coinfectio ...
Elsevier2017Tomographic in vivo microscopy for the study of lung physiology at the alveolar level
Goran Lovric, Marco Stampanoni
Lungs represent the essential part of the mammalian respiratory system, which is reflected in the fact that lung failure still is one of the leading causes of morbidity and mortality worldwide. Establishing the connection between macroscopic observations o ...
2017