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Metabolic contrast agents produced from transported solid C-13-glucose hyperpolarized via dynamic nuclear polarization

Publications associées (35)

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Development and Understanding of Novel Compounds Designed as Potential MRI Contrast Agents

Hugues Jaccard

The two last decades have witnessed the appearance and the successful development of magnetic resonance imaging (MRI) contrast agents (CAs). Though MRI, which has become an essential medical diagnostic tool, can be performed without contrast agents, its ra ...

EPFL2011

Quenching homonuclear couplings in magnetic resonance by trains of non-refocusing pulses

Geoffrey Bodenhausen

Trains of 2pi or 4pi pulses fail to refocus offsets but can suppress the effects of bilinear interactions such as homonuclear scalar couplings. ...

Elsevier2011

Accelerated MR imaging with spread spectrum encoding

Jean-Philippe Thiran, Rolf Gruetter, Pierre Vandergheynst, Dimitri Nestor Alice Van De Ville, Yves Wiaux, José Pedro Rebelo Ferreira Marques, Gilles Puy

We advocate the use of a novel compressed sensing technique for accelerating the magnetic resonance image acquisition process, coined spread spectrum MR imaging or simply s2MRI. The method resides in pre-modulating the signal of interest by a linear chirp, ...

2011

Speeding up Magnetic Resonance Image Acquisition by Bayesian Multi-Slice Adaptive Compressed Sensing

Matthias Seeger

We show how to sequentially optimize magnetic resonance imaging measurement designs over stacks of neighbouring image slices, by performing convex variational inference on a large scale non-Gaussian linear dynamical system, tracking dominating directions o ...

2010

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Major breakthroughs have recently been reported that can help overcome two inherent drawbacks of NMR: the lack of sensitivity and the limited memory of longitudinal magnetization. Dynamic nuclear polarization (DNP) couples nuclear spins to the large reserv ...

2009

Three novel GdDO3A-type bismacrocyclic complexes, conjugated to Ca2+ chelating moieties like ethylenediamine-tetraacetic acid and diethylenetriamine pentaacetic acid bisamides, were synthesized as potential "smart" magnetic resonance imaging contrast agent ...

2008

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A multiple-frequency (9.4-325 GHz) and variable-temperature (276-320 K) electron paramagnetic resonance (EPR) study on low molecular weight gadolinium(III) complexes for potential use as magnetic resonance imaging (MRI) contrast agents has been performed. ...

2007

Magnetic resonance imaging and T2 relaxometry of human median nerve at 7 Tesla

Giulio Gambarota

Measurements of T2 relaxation times in tissues have provided a unique, noninvasive method to investigate the microenvironment of water molecules in vivo. As more clinical imaging is performed at higher field strengths, tissue relaxation times need to be re ...

Wiley-Blackwell2007

New strategies for highly efficient medical MRI contrast agents

Sabrina Laus

During the last two decades, magnetic resonance imaging (MRI) has evolved into one of the most powerful techniques in medical diagnosis. Among the various medical diagnostic modalities, such as X-ray or ultra-sound imaging, MRI is the technique of choice e ...

EPFL2005

In the short time since its introduction, magnetic resonance imaging (MRI) has rapidly evolved to become an indispensable tool for clinical diagnosis and biomedical research. Recently, this methodology has been successfully used for the acquisition of func ...

2000