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Plasma biomarkers for Alzheimer's disease: a field-test in a memory clinic

Publications associées (32)

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Enhancing patient freedom in rehabilitation robotics using gaze-based intention detection

Several design strategies for rehabilitation robotics have aimed to improve patients' experiences using motivating and engaging virtual environments. This paper presents a new design strategy: enhancing patient freedom with a complex virtual environment th ...

IEEE2013

Alzheimer's disease (AD) is a looming threat on an ever-ageing population, with devastating effects on the human intellect. A particular characteristic lesion - the extracellular amyloid plaque - accumulates in the brain of AD patients during the course of ...

Institute of Physics2013

Quantification of brain glucose metabolism by 18F-FDG PET with real-time arterial and image-derived input function in mice

Malte Alf

Kinetic modeling of PET data derived from mouse models remains hampered by the technical inaccessibility of an accurate input function (IF). In this work, we tested the feasibility of IF measurement with an arteriovenous shunt and a coincidence counter in ...

Soc Nuclear Medicine Inc2013

Introduction: beta-Amyloid (A beta) plaques and neurofibrillary tangles are the main characteristics of Alzheimer's disease (AD). Positron emission tomography (PET), a high-resolution, sensitive, and noninvasive imaging technique, has been widely utilized ...

2012

Mathematical Modeling of Brain Energy Metabolism, Measured with PET and MRS in Rodents

Bernard Lanz

Positron emission tomography (PET) and nuclear magnetic resonance spectroscopy (MRS) are two biomedical measurement techniques developed in the end of the XXth century, which drastically improved the amount of accessible information available in vivo. PET ...

EPFL2012

Purpose: To report the lethal course of malignant transformation of retinoma in an adult. Methods: Case report. A 40-year-old patient presented with retinoma in his right eye and retinoblastoma in his left eye. Enucleation was recommended but refused and t ...

Informa Healthcare2012

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3'-deoxy-3'-[F-18]fluorothymidine ([F-18]FLT), a cell proliferation positron emission tomography (PET) tracer, has been shown in numerous tumors to be more specific than 2-deoxy-2-[F-18]fluoro-d-glucose ([F-18]FDG) but less sensitive. We studied the capaci ...

Elsevier2011

Monitoring tumor response to radiation therapy with longitudinal and multimodal molecular imaging

Jessica Perez

Purpose: Metabolic changes induced by radiation therapy (RT) provide a biological measure of tumor response to treatment beyond anatomic changes. In this preclinical study we investigated these changes through longitudinal monitoring of tumor response to v ...

2010

For patients with brain tumors identification of diagnostic and prognostic markers in easy accessible biological material, such as plasma or cerebrospinal fluid (CSF), would greatly facilitate patient management. MIC-1/GDF15 (growth differentiation factor ...

2009

Satisfaction des utilisateurs du dossier patient informatisé valaisan

Philippe Wieser, David Marey

A multidisciplinary and shared computerized patient record (CPR) has been progressively implemented since 2002 for all public hospitals in the State of Valais, Switzerland. This paper presents the results of a formal evaluation of user’s satisfaction ...

2006