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This lecture covers the fundamentals of mechatronics, focusing on actuation, torques, gear transmissions, development teams, and robotics. It explores the design and control of robots, including components like motors, gearboxes, sensors, and mechanical structures. The lecture also delves into the concept of exoskeletons, presenting the TWIICE model and its architecture, control system, and human-machine interface. Additionally, it discusses the importance of actuators in generating efforts, torque capabilities, and the use of reducers to amplify torque. The presentation concludes with a detailed explanation of multi-stage gearboxes, torque calculations, and the integration of motors and reducers in mechatronic systems.