A suicide method is any means by which a person may choose to end their lives. Suicide attempts do not always result in death, and a non-fatal suicide attempt can leave the person with serious physical injuries, long-term health problems, and brain damage.
Worldwide, three suicide methods predominate with the pattern varying in different countries. These are hanging, poisoning by pesticides, and firearms.
Some suicides are impulse decisions that may be preventable by removing the means. Making common suicide methods less accessible leads to an overall reduction in the number of suicides. Some ways to do this include restricting access to pesticides, firearms, and known-used drugs. Other important measures are the introduction of policies that address the misuse of alcohol and the treatment of mental disorders. Gun-control measures in a number of countries have seen a reduction in suicides and other gun-related deaths.
The study of suicide methods aims to identify those commonly used, and the groups at risk of suicide; making methods less accessible may be useful in suicide prevention. Limiting the availability of means such as pesticides and firearms is recommended by a World Health Report on suicide and its prevention. The early identification of mental disorders and substance abuse disorders, follow-up care for those who have attempted suicide, and responsible reporting by the media are all seen to be key in reducing the number of deaths by suicide. National suicide prevention strategies are also advocated using a comprehensive and coordinated response to suicide prevention. This needs to include the registration and monitoring of suicides and attempted suicide, breaking figures down by age, sex, and method.
Such information allows public health resources to focus on the problems that are relevant in a particular place, or for a given population or subpopulation. For instance, if firearms are used in a significant number of suicides in one place, then public health policies there could focus on gun safety, such as keeping guns locked away, and the key inaccessible to at-risk family members.
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Closely interfacing with bioengineering and medicine, this course provides foundational concepts in applying small-molecule chemical toolsets to probe the functions of living systems at the mechanisti
Suicide is the act of intentionally causing one's own death. Mental disorders (including depression, bipolar disorder, schizophrenia, personality disorders, anxiety disorders), physical disorders (such as chronic fatigue syndrome), and substance abuse (including alcoholism and the use of and withdrawal from benzodiazepines) are risk factors. Some suicides are impulsive acts due to stress (such as from financial or academic difficulties), relationship problems (such as breakups or divorces), or harassment and bullying.
Advocacy of suicide, also known as pro-suicide, has occurred in many cultures and subcultures. Confucianism holds that one should give up one's life, if necessary, either passively or actively, for the sake of upholding the cardinal moral values of ren (altruism) and yi (righteousness). The Japanese military during World War II encouraged and glorified kamikaze attacks, and Japanese society as a whole has been described as "suicide-tolerant" (see Suicide in Japan). Advocacy of suicide has also taken place over the Internet.
In ethics and other branches of philosophy, suicide poses difficult questions, answered differently by various philosophers. The French Algerian essayist, novelist, and playwright Albert Camus (1913–1960) began his philosophical essay The Myth of Sisyphus with the famous line "There is but one truly serious philosophical problem and that is suicide." (Il n'y a qu'un problème philosophique vraiment sérieux : c'est le suicide.). Philosophical stances on suicide can be divided into two broad groups.
Covers enzyme inhibition mechanisms, drug modes of action, targeted protein degradation using PROTACs, and the bump-hole method for protein-ligand engineering.
Delves into the efficacy of covalent drugs in chemical biology, exploring reversible vs. irreversible binders and mechanism-based inactivators.
Covers basic probability theory, ANOVA, experimental design, and correlations, emphasizing the importance of planning multiple tests and power analysis.
We study the effect of starting point and self-consistency within GW on the band-edge positions of semiconductors and insulators. Compared to calculations based on a semilocal starting point, the use of a hybrid-functional starting point shows a larger qua ...