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Drug discovery

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Delves into the fundamentals of medicinal chemistry, emphasizing the interrogation of Structure-Activity Relationships (SAR) in drug design.

Interrogating SAR: Medicinal Chemistry

Covers medicinal chemistry basics, high-throughput screening, lead discovery milestones, and compound selectivity in drug optimization.

Fragment-Based Drug Discovery: Concepts & Technologies

Covers the concepts and technologies of fragment-based drug discovery, exploring hit identification, lead optimization, and screening methods.

Pharmacodynamics: Ligand-Receptor Binding and Drug Effects

Explores ligand-receptor binding, drug effects, efficacy, potency, and biased agonism in pharmacodynamics.

Chemical Biology: High-Throughput and High-Content Screening

Covers Chemical Biology, high-throughput screening, RNA interference, CRISPR-Cas9, and organoid differentiation for drug discovery.

Drug Discovery: Computational Approaches

Explores the EXSCALATE4COV project, focusing on computational drug discovery for COVID-19 treatments and the collaboration between academia and industry.

Fragment-Based Drug Discovery: Concepts & Technologies

Covers the concepts and technologies of fragment-based drug discovery, hit identification methods, and its application in target-based drug discovery.

The ClpXP Proteolytic Complex: Basic Principles to Drug Discovery

Explores the ClpXP proteolytic complex, its drug targeting potential, and antimicrobial applications through compound screening.

Pharmacodynamics: Ligand-Receptor Interactions and Drug Effects

Explores ligand-receptor interactions, drug effects, modulation mechanisms, and factors influencing drug responses.

Pharmacodynamics: Ligand Concentration, Binding, and Effect

Explores the relationship between ligand concentration, binding, and effect, focusing on allosteric modulators and types of pharmacological antagonists.