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Smoking is a practice in which a substance is combusted and the resulting smoke is typically inhaled to be tasted and absorbed into the bloodstream of a person. Most commonly, the substance used is the dried leaves of the tobacco plant, which have been rolled with a small rectangle of paper into an elongated cylinder called a cigarette. Other forms of smoking include the use of a smoking pipe or a bong. Smoking is primarily practised as a route of administration for psychoactive chemicals because the active substances within the burnt dried plant leaves vaporizes and can be airborne-delivered into the respiratory tract, where they are rapidly absorbed into the bloodstream of the lungs and then reach the central nervous system. In the case of tobacco smoking, these active substances are a mixture of aerosol particles that includes the pharmacologically active alkaloid nicotine, which stimulates the nicotinic acetylcholine receptors in the brain. Other notable active substances inhaled via smoking include tetrahydrocannabinol (from cannabis), morphine (from opium) and cocaine (from crack). In some cultures, smoking is also carried out as a part of various rituals, where participants use it to help induce trance-like states that, they believe, can lead them to spiritual enlightenment. Smoking is one of the most common forms of recreational drug use. Tobacco smoking is the most popular form, being practised by over one billion people globally, of whom the majority are in the developing countries. Less common drugs for smoking include cannabis and opium. Some of the substances are classified as hard narcotics, like heroin, but the use of these is very limited as they are usually not commercially available. Cigarettes are primarily industrially manufactured but also can be hand-rolled from loose tobacco and rolling paper. Other smoking implements include pipes, cigars, bidis, hookahs, and bongs. Smoking has negative health effects, because smoke inhalation inherently poses challenges to various physiologic processes such as respiration.
Michael Herzog, Simona Adele Garobbio
Stéphane Joost, Idris Guessous, David Nicolas De Ridder