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Related lectures (12)

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Pharmacokinetics: Drug Absorption and Distribution

Explores drug absorption, distribution, and clinical implications, focusing on salicylate poisoning and drug trapping in lysosomes.

Identifying Correct Target in Medical Chemistry

Explores target identification, efficacy, and safety in medical chemistry, emphasizing the importance of on-target specificity and drug design.

Pharmacological Targets and Interventions

Explores targets for drug action and the design of specific inhibitors.

Interrogating Drugs' Mode of Action

Delves into enzyme inhibition, reversible and irreversible binding, and covalent drugs, exploring drug modes of action and their impact on drug efficacy.

Machine Learning-Guided Treatment Discovery

Explores personalized medicine, machine learning for treatment prediction, and challenges in traditional algorithms.

SEGREGATION of KINETIC REACTIVITY & BINDING AFFINITY

The paper focuses on the importance of reversible interactions to potency and mechanisms of drug resistance.

Pharmacokinetic & Pharmacodynamic Evaluations

Covers the principles of pharmacokinetics and pharmacodynamics, including drug exposure-response relationships.

Pharmacokinetics Modeling: Zero and First-Order Kinetics

Explores pharmacokinetics modeling, covering zero and first-order kinetics, drug distribution, and key parameters for drug elimination.

Engineering brain activity patterns for therapeutics

Discusses correcting aberrant brain-wide activity patterns using distinct network motifs and neuromodulators.

Neurotransmitters: Receptors and Effects

Explores major neurotransmitters, their effects, drug therapy, and receptor mechanisms in brain function.