An interstellar cloud is generally an accumulation of gas, plasma, and dust in our and other galaxies. Put differently, an interstellar cloud is a denser-than-average region of the interstellar medium, the matter and radiation that exists in the space between the star systems in a galaxy. Depending on the density, size, and temperature of a given cloud, its hydrogen can be neutral, making an H I region; ionized, or plasma making it an H II region; or molecular, which are referred to simply as molecular clouds, or sometime dense clouds. Neutral and ionized clouds are sometimes also called diffuse clouds. An interstellar cloud is formed by the gas and dust particles from a red giant in its later life.
The chemical composition of interstellar clouds is determined by studying electromagnetic radiation that they emanate, and we receive – from radio waves through visible light, to gamma rays on the electromagnetic spectrum – that we receive from them. Large radio telescopes scan the intensity in the sky of particular frequencies of electromagnetic radiation, which are characteristic of certain molecules' spectra. Some interstellar clouds are cold and tend to give out electromagnetic radiation of large wavelengths. A map of the abundance of these molecules can be made, enabling an understanding of the varying composition of the clouds. In hot clouds, there are often ions of many elements, whose spectra can be seen in visible and ultraviolet light.
Radio telescopes can also scan over the frequencies from one point in the map, recording the intensities of each type of molecule. Peaks of frequencies mean that an abundance of that molecule or atom is present in the cloud. The height of the peak is proportional to the relative percentage that it makes up.
Until recently, the rates of reactions in interstellar clouds were expected to be very slow, with minimal products being produced due to the low temperature and density of the clouds. However, organic molecules were observed in the spectra that scientists would not have expected to find under these conditions, such as formaldehyde, methanol, and vinyl alcohol.