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Development of a nano-adjuvant cancer vaccine and its evaluation for melanoma in combination with radiotherapy

Sylvie Hauert

Cancer is the second leading cause of death in the world and melanoma is the deadliest type of skin cancer. Although surgery, radiotherapy and chemotherapy are still standard treatments, the discovery of the role played by the immune system in cancer has a ...

EPFL2018

Activation Inventories After Exposure To Dd/Dt Neutrons In Safety Analysis Of Nuclear Fusion Installations

Olivier Sauter, Ambrogio Fasoli, Basil Duval, Stefano Coda, Martinus Gijs, Jonathan Graves, Yves Martin, Duccio Testa, Patrick Blanchard, Bruno Emanuel Ferreira De Sousa Correia

Irradiations with 14 MeV fusion neutrons are planned at Joint European Torus (JET) in DT operations with the objective to validate the calculation of the activation of structural materials in functional materials expected in ITER and fusion plants. This st ...

2018

A Radiation-Tolerant, high performance SPAD for SiPMs implemented in CMOS technology

Edoardo Charbon, Myung Jae Lee, Qi Guo

We investigate the radiation effects on single-photon avalanche diodes (SPADs) fabricated in CMOS technology. For this investigation, a high-performance SPAD based on a vertical p-i-n construction with buried-N layer is proposed and used for the characteri ...

2017

Total ionizing dose effects on a 28 nm Hi-K metal-gate CMOS technology up to 1 Grad

Chunmin Zhang, Alessandro Pezzotta

This paper presents the results of an irradiation study on single transistors manufactured in a 28 nm high-k commercial CMOS technology up to 1 Grad. Both nMOSFET and pMOSFET transistors have been irradiated and electrical parameters have been measured. Fo ...

2017

The radiation field in the Gamma Irradiation Facility GIF plus plus at CERN

Georgi Gorine, Federico Ravotti

The high-luminosity LHC (HL-LHC) upgrade is setting now a new challenge for particle detector technologies. The increase in luminosity will produce a particle background in the gas-based muon detectors that is ten times higher than under conditions at the ...

2017

GigaRad total ionizing dose and post-irradiation effects on 28 nm bulk MOSFETs

Christian Enz, Claudio Bruschini, Farzan Jazaeri, Chunmin Zhang, Alessandro Pezzotta, Federico Faccio

The DC performance of both n- and pMOSFETs fabricated in a commercial-grade 28 nm bulk CMOS process has been studied up to 1 Grad of total ionizing dose and at post-irradiation annealing. The aim is to assess the potential use of such an advanced CMOS tech ...

IEEE2016

FeOx-TiO2 Film with Different Microstructures Leading to Femtosecond Transients with Different Properties: Biological Implications under Visible Light

César Pulgarin, Juan Kiwi, Sami Rtimi

This study presents the first report addressing the effect of FeOx-TiO2 films microstructure on the transients detected by fast spectroscopy related to the long-range bacterial inactivation performance. The different fast kinetic femtosecond transient spec ...

Nature Research2016

Fast 3D reconstruction method for differential phase contrast X-ray CT

Michaël Unser, Masih Nilchian, Michael Thompson McCann, Marco Stampanoni

We present a fast algorithm for fully 3D regularized X-ray tomography reconstruction for both traditional and differential phase contrast measurements. In many applications, it is critical to reduce the X-ray dose while producing high-quality reconstructio ...

2016

Integrated Photo-Electrochemical Solar Fuel Generators under Concentrated Irradiation- Part I: 2-D Non-Isothermal Multiphysics Modelling

Sophia Haussener, Saurabh Yuvraj Tembhurne

We investigate the direct conversion of solar energy and water into a storable fuel via integrated photo-electrochemical (IPEC) devices. Here we focus particularly on a device design which uses concentrated solar irradiation to reduce the use of rare and e ...

Electrochemical Society2016

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Development of a nano-adjuvant cancer vaccine and its evaluation for melanoma in combination with radiotherapy

Sylvie Hauert

EPFL2018

A Radiation-Tolerant, high performance SPAD for SiPMs implemented in CMOS technology

Edoardo Charbon, Myung Jae Lee, Qi Guo

2017

FeOx-TiO2 Film with Different Microstructures Leading to Femtosecond Transients with Different Properties: Biological Implications under Visible Light

César Pulgarin, Juan Kiwi, Sami Rtimi

Nature Research2016

Integrated Photo-Electrochemical Solar Fuel Generators under Concentrated Irradiation- Part I: 2-D Non-Isothermal Multiphysics Modelling

Sophia Haussener, Saurabh Yuvraj Tembhurne

Electrochemical Society2016