Concept

Fluorescence in situ hybridization

Related publications (222)

On the Applicability of Oil and Dye Technique During the Design Phase and Operation of Experimental Rigs

In this paper, an oil and dye flow visualization technique applied in two different cases of experimental testing is described, namely a single fan in crossflow and the wake of a compressor cascade. In both cases, the mixture of paint was prepared using a ...

2011

Detecting long-range chromatin interactions using the chromosome conformation capture sequencing (4C-seq) method

Jacques Rougemont, Marion Leleu, Nele Gheldof, Daniël Noordermeer

Eukaryotic transcription is tightly regulated by transcriptional regulatory elements, even though these elements may be located far away from their target genes. It is now widely recognized that these regulatory elements can be brought in close proximity t ...

Springer Science+Business Media2011

Genomic instability in induced stem cells

Didier Trono, Marc Samuel Friedli

The ability to reprogram adult cells into stem cells has raised hopes for novel therapies for many human diseases. Typical stem cell reprogramming protocols involve expression of a small number of genes in differentiated somatic cells with the c-Myc and Kl ...

Nature Publishing Group2011

Insight into the Regulation of Telomerase Access to Telomeres by Shelterin Proteins

Elena Aritonovska

Recruitment to telomeres is a pivotal step in the function and regulation of human telomerase. Impaired telomerase function can lead to premature organismal aging, development of cancer and multisystem disorders such as dyskeratosis congenita. Telomerase a ...

EPFL2011

A Time-Gated 128x128 CMOS SPAD Array for on-Chip Fluorescence Detection

Edoardo Charbon

An all-digital, time-gated 128x128 CMOS image sensor for on-chip fluorescence detection is presented. The sensor pixel consists of a single-photon avalanche diode (SPAD), time gating circuitry and a 1bit memory. The sensor allows on-chip fluorescence detec ...

2011

Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast

Joachim Lingner, Sophie Redon, Verena Pfeiffer, Nahid Iglesias

Telomeric repeat-containing RNA (TERRA) has been implicated in the control of heterochromatin and telomerase. We demonstrate that yeast TERRA is regulated by telomere-binding proteins in a chromosome-end-specific manner that is dependent on subtelomeric re ...

2011

Evaluating Gene Expression Dynamics Using Pairwise RNA FISH Data

Matthieu Wyart

Recently, a novel approach has been developed to study gene expression in single cells with high time resolution using RNA Fluorescent In Situ Hybridization (FISH). The technique allows individual mRNAs to be counted with high accuracy in wildtype cells, b ...

Public Library of Science2010

Cell Morphology and Intracellular Ionic Homeostasis explored with a Multimodal Approach combining Epifluorescence and Digital Holographic Microscopy

Pierre Magistretti, Christian Depeursinge, Nicolas Pavillon, Pierre Marquet, Jonas Kühn, Pascal Jourdain, Daniel Boss, Aleksandr Benke, Corinne Moratal

The authors have developed a live-cell multimodality microscope combining epifluorescence with digital holographic microscopy; it has been implemented with a decoupling procedure allowing to separately measure from the quantitative phase important cell par ...

2010

A Male with Unilateral Microphthalmia Reveals a Role for TMX3 in Eye Development

Yao Zhang, Pooja Agarwal

Anophthalmia and microphthalmia are important birth defects, but their pathogenesis remains incompletely understood. We studied a patient with severe unilateral microphthalmia who had a 2.7 Mb deletion at chromosome 18q22.1 that was inherited from his moth ...

Public Library of Science2010

Microelectronics Meets Biology

Emile Dupont

Microfluidics plays a key role in the design of automated platforms for realizing biological assays in a miniaturized format. Several advantages are offered by a microfluidic system, namely, low sample and reagent consumption (typically a few microliters), ...

EPFL2010

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.