Regular expression | EPFL Graph Search

A regular expression (shortened as regex or regexp; sometimes referred to as rational expression) is a sequence of characters that specifies a match pattern in text. Usually such patterns are used by string-searching algorithms for "find" or "find and replace" operations on strings, or for input validation. Regular expression techniques are developed in theoretical computer science and formal language theory. The concept of regular expressions began in the 1950s, when the American mathematician Stephen Cole Kleene formalized the concept of a regular language. They came into common use with Unix text-processing utilities. Different syntaxes for writing regular expressions have existed since the 1980s, one being the POSIX standard and another, widely used, being the Perl syntax. Regular expressions are used in search engines, in search and replace dialogs of word processors and text editors, in text processing utilities such as sed and AWK, and in lexical analysis. Regular expression

Mens Sana in Corpore Sano

Christophe Alhanko, Simon Zangger

Lieu dédié au corps et à l'esprit, le programme est déterminé par des objectifs multiples propices à l'exercice physique et à la flânerie. Bains, piscines et équipements sportifs se regroupent pour former une nouvelle condition, sorte d'exutoire au sein d'un campus en effervescence. En pleine expansion, le parc universitaire rejette peu à peu la responsabilité des activités annexes aux initiatives personnelles et préférablement hors de son enceinte. La pression engendrée par la prolifération de nouvelles constructions pose la question d'un retour vers un équilibre programmatique et force à concevoir un lieu exclusivement consacré aux loisirs, tel un dernier bastion, sanctuaire du bien-être personnel et social. Poussée jusqu'aux frontières du centre sportif universitaire, l'intervention transgresse les limites territoriales, prenant l'allure d'un finistère, point de repère d'un spectacle spatial entre forêt, parcs et quartier résidentiel. S'inscrivant dans une logique successive de bâtiments pavillonnaires, il dialogue avec les autres icônes qu'il côtoie, tout en offrant au territoire de l'Ouest lausannois une infrastructure publique à l'image de ses voisines métropolitaines: Bellerive-Plage et Bains des Pâquis. La figure géométrique restructure les espaces résiduels du site. Sa perception varie selon les usages et les aléas saisonniers. La disposition diagrammatique des éléments ainsi que la topographie accentuent son caractère de paysage architectural. L'expression de l'ensemble revêt un caractère brutaliste, s'inscrivant ainsi dans la tradition des grandes infrastructures modernes lémaniques.

2016

Overexpression of the human antigen R suppresses the immediate paradoxical proliferation of melanoma cell subpopulations in response to suboptimal BRAF inhibition

Christoph Schwärzler

Tumor plasticity and the heterogeneous response of melanoma cells to targeted therapies are major limits for the long-term efficacy of this line of therapy. Targeting tumor plasticity is theoretically possible through the modulation of the expression of RNA-binding proteins which can affect many different compensatory mechanisms of the adaptive response of malignant cells to targeted therapies. Human antigen R (HuR) is a modulator of gene expression and a transacting factor in the mRNA-processing machinery used in the cell stress response, and is a potential target for reducing tumor plasticity. In this experiment, we exploit the inherent heterogeneous response of the A375 melanoma line to suboptimal BRAF inhibition as a model of immediate adaptive response. We first observe that HuR overexpression can prevent the heterogeneous response and thus the immediate paradoxical proliferation induced by low-doses vemurafenib treatment. We then use single-cell mass cytometry to characterize subpopulations, including those that paradoxically proliferate, based on their proliferation rate and the expression patterns of markers involved in the reversible adaptive resistance to BRAF inhibition and/or recognized as HuR targets involved in cell cycle regulation. Under suboptimal BRAF inhibition, HuR overexpression affects these subpopulations and their expression pattern with contrasting responses depending on their proliferation rate: faster-proliferating vemurafenib-sensitive or -resistant subpopulations showed higher death tendency and reduced size, and slower-proliferating subpopulations showed an attenuated resistant expression response and their paradoxical proliferation was inhibited. These observations pave the way to new therapeutic strategies for preventing the heterogeneous response of tumors to targeted therapies.

Wiley2017

Quote Erat Demonstrandum: AWeb Interface for Exploring the Quotebank Corpus

Akhil Arora, Huan-Cheng Chang, Andreas Oliver Spitz, Vuk Vukovic, Robert West

The use of attributed quotes is the most direct and least filtered pathway of information propagation in news. Consequently, quotes play a central role in the conception, reception, and analysis of news stories. Since quotes provide a more direct window into a speaker's mind than regular reporting, they are a valuable resource for journalists and researchers alike. While substantial research efforts have been devoted to methods for the automated extraction of quotes from news and their attribution to speakers, few comprehensive corpora of attributed quotes from contemporary sources are available to the public. Here, we present an adaptive web interface for searching Quotebank, a massive collection of quotes from the news, which we make available at https://quotebank.dlab.tools.

ASSOC COMPUTING MACHINERY2022

Overexpression of the human antigen R suppresses the immediate paradoxical proliferation of melanoma cell subpopulations in response to suboptimal BRAF inhibition

Christoph Schwärzler

Wiley2017