Research reactors are nuclear fission-based nuclear reactors that serve primarily as a neutron source. They are also called non-power reactors, in contrast to power reactors that are used for electricity production, heat generation, or maritime propulsion. The neutrons produced by a research reactor are used for neutron scattering, non-destructive testing, analysis and testing of materials, production of radioisotopes, research and public outreach and education. Research reactors that produce radioisotopes for medical or industrial use are sometimes called isotope reactors. Reactors that are optimised for beamline experiments nowadays compete with spallation sources. Research reactors are simpler than power reactors and operate at lower temperatures. They need far less fuel, and far less fission products build up as the fuel is used. On the other hand, their fuel requires more highly enriched uranium, typically up to 20% U-235, although some use 93% U-235; while 20% enrichment is not generally considered usable in nuclear weapons, 93% is commonly referred to as "weapons-grade". They also have a very high power density in the core, which requires special design features. Like power reactors, the core needs cooling, typically natural or forced convection with water, and a moderator is required to slow the neutron velocities and enhance fission. As neutron production is their main function, most research reactors benefit from reflectors to reduce neutron loss from the core. The International Atomic Energy Agency and the U.S. Department of Energy initiated a program in 1978 to develop the means to convert research reactors from using highly enriched uranium (HEU) to the use of low enriched uranium (LEU), in support of its nonproliferation policy. By that time, the U.S. had supplied research reactors and highly enriched uranium to 41 countries as part of its Atoms for Peace program. In 2004, the U.S. Department of Energy extended its Foreign Research Reactor Spent Nuclear Fuel Acceptance program until 2019.

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