Concept

Single-photon emission computed tomography

Related publications (183)

Fabrication and Characterization of High Aspect Ratio Amorphous Silicon Based Microchannel Plates

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This contribution focuses on the fabrication and characterization of microchannel plates made of hydrogenated amorphous silicon (AMCPs). Flexible fabrication processes and the semi-conducting nature of amorphous silicon could give these detectors the advan ...

2021

Large-Format Time-Gated SPAD Cameras for Real-Time Phasor-Based FLIM

Arin Can Ülkü

Fluorescence lifetime imaging microscopy (FLIM) is an imaging modality often used to monitor biochemical properties of a cell or a tissue. In addition to conventional fluorescence microscopy features, such as selective labeling and non-invasiveness, FLIM e ...

EPFL2021

Far field superlensing inside biological media through a nanorod lens using spatiotemporal information

Anja Skrivervik

Far field superlensing of light has generated great attention in optical focusing and imaging applications. The capability of metamaterials to convert evanescent waves to propagative waves has led to numerous proposals in this regard. The common drawback o ...

2021

Roadmap toward the 10 ps time-of-flight PET challenge

Edoardo Charbon, Mathieu Benoit, Christian Morel, Joao Varela

Since the seventies, positron emission tomography (PET) has become an invaluable medical molecular imaging modality with an unprecedented sensitivity at the picomolar level, especially for cancer diagnosis and the monitoring of its response to therapy. Mor ...

IOP PUBLISHING LTD2020

Methods and apparatus for tomographic additive manufacturing with a spatially coherent light source

Christophe Moser, Paul Delrot, Damien Claude-Marie Loterie

A method of fabricating a three-dimensional article comprises providing a spatially coherent light source (101, 201), generating from said light source (101, 201), patterns of light based on computed tomographic projections of said three-dimensional articl ...

2020

Image Clustering Algorithms to Identify Complicated Cerebral Diseases. Description and Comparison

Maria-Alexandra Paun

This article presents two algorithms developed based on two different techniques, from clusterization theory, namely k-means clustering technique and Fuzzy C-means technique, respectively. In this context, the study offers a sustained comparison of the two ...

2020

Development of novel tools for imaging of metabolic fluxes in vivo

Tamara Maric

Bioluminescent imaging is a powerful technique that enables imaging in living organisms with high sensitivity, low background signal, low cost and without the need for radioactivity. The emitted photons are produced in the oxidation reaction of luciferin c ...

EPFL2020

Toward Bright and Pure Single Photon Emitters at 300 K Based on GaN Quantum Dots on Silicon

Nicolas Grandjean, Raphaël Butté, Johann Nicolaï Stachurski, Gordon Jens Callsen, Sebastian Pascal Tamariz Kaufmann, Kanako Shojiki

Quantum dots (QDs) based on III-nitride semi-conductors are promising for single photon emission at noncryogenic temperatures due to their large exciton binding energies. Here, we demonstrate GaN QD single photon emitters operating at 300 K with g((2)) (0) ...

AMER CHEMICAL SOC2020

Model-informed machine learning for multi-component T2 relaxometry

Jean-Philippe Thiran, Meritxell Bach Cuadra, Tobias Kober, Tom Hilbert, Erick Jorge Canales Rodriguez, Elda Fischi Gomez, Marco Pizzolato, Gian Franco Piredda, Thomas Yu, Cristina Granziera, Muhamed Barakovic

Recovering the distribution from multi-echo magnetic resonance (MR) signals is challenging but has high potential as it provides biomarkers characterizing the tissue micro-structure, such as the myelin water fraction (MWF). In this work, we propose to comb ...

2020

Megapixel time-gated SPAD image sensor for 2D and 3D imaging applications

Edoardo Charbon, Claudio Bruschini, Ivan Michel Antolovic, Andrei Ardelean, Ming-Lo Wu, Arin Can Ülkü, Kazuhiro Morimoto

We present a 1 Mpixel single-photon avalanche diode camera featuring 3.8 ns time gating and 24 kips frame rate, fabricated in 180 nm CMOS image sensor technology. We designed two pixels with a pitch of 9.4 mu m in 7 T and 5.75 T configurations respectively ...

OPTICAL SOC AMER2020

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