Concept

Trial

Related publications (26)

Association between endocrine adjuvant therapy intake timing and disease-free survival in patients with high-risk early breast cancer: results of a sub-study of the UCBG- UNIRAD trial

Background Circadian rhythms regulate cellular physiology and could in fl uence the ef fi cacy of endocrine therapy (ET) in breast cancer (BC). We prospectively tested this hypothesis within the UNIRAD adjuvant phase III trial (NCT01805271). Methods 1278 p ...

Elsevier2024

Targeting the Progesterone Receptor in Breast Cancer: Mind the Short Form!

Cathrin Brisken, Carlos Henrique Venturi Ronchi

The presurgical window of opportunity trial (WOT) MIPRA provides evidence that neoadjuvant treatment with the prog-esterone receptor (PR) antagonist mifepristone (RU486) may benefit patients with estrogen receptor-positive (ER+) breast cancer characterized ...

AMER ASSOC CANCER RESEARCH2023

Cell administration routes for heart failure: a comparative re-evaluation of the REGENERATE-DCM and REGENERATE-IHD trials

Didier Locca

Aims: Given the logistical issues surrounding intramyocardial cell delivery, we sought to address the efficacy of the simpler, more accessible intracoronary route by re-evaluating REGENERATE-DCM and REGENERATE-IHD (autologous cell therapy trials for heart ...

FUTURE MEDICINE LTD2022

Perceptual decisions under stable visual input: absence of serial dependence and the build-up of adaptation

Michael Herzog, David Pascucci, Alice Biryukov, Gizay Ceylan

In serial dependence (SD), perceptual decisions are biased toward stimuli seen in the recent past. It is believed that SD originates from a perceptual prior that the world is stable and stimuli are correlated in time. Often, however, SD is observed in cond ...

2021

Adaptive Task-Space Force Control for Humanoid-to-Human Assistance

Anastasia Bolotnikova

We envision a humanoid robot to serve as a source of additional motion-support forces in assistance for frail persons. In this context, we present a control strategy for a humanoid to adaptively regulate its assistive force contribution. First, we identify ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2021

Clustering and control for adaptation uncovers time-warped spike time patterns in cortical networks in vivo

James Bryden Isbister

How information in the nervous system is encoded by patterns of action potentials (i.e. spikes) remains an open question. Multi-neuron patterns of single spikes are a prime candidate for spike time encoding but their temporal variability requires further c ...

2021

Intent Prediction Based on Biomechanical Coordination of EMG and Vision-Filtered Gaze for End-Point Control of an Arm Prosthesis

Aude Billard, Silvestro Micera, Iason Batzianoulis, Nili Eliana Krausz

We propose a novel controller for powered prosthetic arms, where fused EMG and gaze data predict the desired end-point for a full arm prosthesis, which could drive the forward motion of individual joints. We recorded EMG, gaze, and motion-tracking during p ...

2020

Rapid Recalibration of Peri-Personal Space: Psychophysical, Electrophysiological, and Neural Network Modeling Evidence

Olaf Blanke, Bruno Herbelin, Andrea Serino, Jean-Paul Noel, Elisa Pellencin, Tommaso Enrico Bertoni

Interactions between individuals and the environment occur within the peri-personal space (PPS). The encoding of this space plastically adapts to bodily constraints and stimuli features. However, these remapping effects have not been demonstrated on an ada ...

2020

Probing Context-Dependent Modulations of Ipsilateral Premotor-Motor Connectivity in Relapsing-Remitting Multiple Sclerosis

Estelle Emeline Raffin

Objective: We employed dual-site TMS to test whether ipsilateral functional premotor-motor connectivity is altered in relapsing-remitting Multiple Sclerosis (RR-MS) and is related to central fatigue. Methods: Twelve patients with RR-MS and 12 healthy contr ...

FRONTIERS MEDIA SA2020

Low Carbon Cement LC3 in Cuba: Ways to Achieve a Sustainable Growth of Cement Production in Emerging Economies

Karen Scrivener

Through a collaborative work established between CIDEM and the Laboratory of Construction Materials at EPFL, a new cementitious system based on a synergetic combination of calcined clay and limestone as Portland's clinker replacement was developed. The nov ...

SPRINGER2018

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