Staggered conformation

About
Privacy
Disclaimer

Graph Chatbot

Related publications (21)

Conformational control of anticancer activity: the application of arene-linked dinuclear ruthenium(II) organometallics

Paul Joseph Dyson, Rosario Scopelliti, Laure Menin, Benjamin Samuel Murray

Dinuclear metal complexes have emerged as a promising class of biologically active compounds which possess unique anticancer activity. Here, we describe a novel series of arene-linked dinuclear organometallic Ru(II) complexes, where the relative conformati ...

2014

Direct Evaluation of the Hyperconjugative Interactions in 1,1,1-Trihaloethane (CH3CX3, X = F, Cl, and Br)

Anne-Clémence Corminboeuf, Zhenhua Chen

Following the computational strategy proposed by Mulliken in 1939 (J. Chem. Phys. 1939, 7 (5), 339-352), when the concept of hyperconjugation was coined, we evaluated the hyperconjugative stabilization energy in 1,1,1-trihaloethane using the block-localize ...

Amer Chemical Soc2014

Increasing the Efficiency of Ligands for FK506-Binding Protein 51 by Conformational Control

Ranganath Gopalakrishnan

The design of efficient ligands remains a key challenge in drug discovery. In the quest for lead-like ligands for the FK506-binding protein 51 (FKBP51), we designed two new classes of bicyclic sulfonamides to probe the contribution of conformational energy ...

Amer Chemical Soc2013

Semisynthetic Fluorescent Sensor Proteins Based on Self-Labeling Protein Tags

Matthias Albert Brun

Genetically encoded fluorescent sensor proteins offer the possibility to probe the concentration of key metabolites in living cells. The approaches currently used to generate such fluorescent sensor proteins lack generality, as they require a protein that ...

EPFL2011

Characterization of the Flow Generated in an Annular Test Facility

Peter Ott, Elia Colombo, Dominique Charbonnier, Cécile Deslot

Annular cascades are particularly useful to study the three dimensional phenomena encountered in turbomachines. The Non-Rotating Annular Test Facility of the Swiss Federal Institute of Technology in Lausanne (EPFL) consists in a radial-axial inlet nozzle a ...

2011

Semisynthetic fluorescent sensor proteins based on self-labeling protein tags

Kai Johnsson, Marlon Hinner, Matthias Albert Brun, Kui Thong Tan

Genetically encoded fluorescent sensor proteins offer the possibility to probe the concentration of key metabolites in living cells. The approaches currently used to generate Such fluorescent sensor proteins lack. generality, as they require a protein that ...

2009

Spectroscopic studies of cold, gas-phase biomolecular ions

Thomas Rizzo, Oleg Boyarkine

While the marriage of mass spectrometry and laser spectroscopy is not new, developments over the last few years in this relationship have opened up new horizons for the spectroscopic study of biological molecules. The combination of electrospray ionization ...

2009

Multiple-resonance spectroscopy of high vibrational levels in water and methanol

Pavlo Maksyutenko

We have measured the rovibrational levels in the electronic ground state of the water molecule at the previously inaccessible energies above 26000 cm-1. The use of laser double-resonance overtone excitation combined with laser-induced fluorescence (LIF) ph ...

EPFL2008

State-specific studies of internal mixing in a prototypical flexible bichromophore: Diphenylmethane

Laser-induced fluorescence, resonant two-photon ionization, UV-UV hole burning, UV depletion, and single vibronic level fluorescence (SVLF) spectra of jet-cooled diphenylmethane (DPM) have been recorded over the 37 300 - 38 400 cm(-1) region that encompass ...

2008

Conformational dependence of intramolecular vibrational redistribution in methanol

Thomas Rizzo, Oleg Boyarkine, Pavlo Maksyutenko

Previous state-selected spectra of methanol in the 5ν1 OH stretch overtone region [O. V. Boyarkin, T. R. Rizzo, and D. S. Perry, J. Chem. Phys. 110 (23), 11346 (1999)] revealed structure indicating intramolecular vibrational redistribution (IVR) on three t ...

2007

Page 2 of 3

Direct Evaluation of the Hyperconjugative Interactions in 1,1,1-Trihaloethane (CH3CX3, X = F, Cl, and Br)

Anne-Clémence Corminboeuf, Zhenhua Chen

Amer Chemical Soc2014

Semisynthetic fluorescent sensor proteins based on self-labeling protein tags

Kai Johnsson, Marlon Hinner, Matthias Albert Brun, Kui Thong Tan

Genetically encoded fluorescent sensor proteins offer the possibility to probe the concentration of key metabolites in living cells. The approaches currently used to generate Such fluorescent sensor proteins lack. generality, as they require a protein that ...

2009