Concept

Respiratory droplet

Summary
A respiratory droplet is a small aqueous droplet produced by exhalation, consisting of saliva or mucus and other matter derived from respiratory tract surfaces. Respiratory droplets are produced naturally as a result of breathing, speaking, sneezing, coughing, or vomiting, so they are always present in our breath, but speaking and coughing increase their number. Droplet sizes range from < 1 μm to 1000 μm, and in typical breath there are around 100 droplets per litre of breath. So for a breathing rate of 10 litres per minute this means roughly 1000 droplets per minute, the vast majority of which are a few micrometres across or smaller. As these droplets are suspended in air, they are all by definition aerosols. However, large droplets (larger than about 100 μm, but depending on conditions) rapidly fall to the ground or another surface and so are only briefly suspended, while droplets much smaller than 100 μm (which is most of them) fall only slowly and so form aerosols with lifetimes of minutes or more, or at intermediate size, may initially travel like aerosols but at a distance fall to the ground like droplets ("jet riders"). These droplets can contain infectious bacterial cells or virus particles they are important factors in the transmission of respiratory diseases. In some cases, in the study of disease transmission a distinction between what are called "respiratory droplets" and what are called "aerosols" is made, with only larger droplets referred to as "respiratory droplets" and smaller ones referred to as "aerosols" but this arbitrary distinction has never been supported experimentally or theoretically, and is not consistent with the standard definition of an aerosol. Respiratory droplets from humans include various cells types (e.g. epithelial cells and cells of the immune system), physiological electrolytes contained in mucous and saliva (e.g. Na+, K+, Cl−), and, potentially, various pathogens. Droplets that dry in the air become droplet nuclei which float as aerosols and can remain suspended in air for considerable periods of time.
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