Concept

Hippocampus

Related publications (246)

Impact of Caffeine Consumption on Type 2 Diabetes-Induced Spatial Memory Impairment and Neurochemical Alterations in the Hippocampus

Rolf Gruetter, João Miguel das Neves Duarte

Diabetes affects the morphology and plasticity of the hippocampus, and leads to learning and memory deficits. Caffeine has been proposed to prevent memory impairment upon multiple chronic disorders with neurological involvement. We tested whether long-term ...

2019

Pituitary dysmaturation affects psychopathology and neurodevelopment in 22q11.2 Deletion Syndrome

Dimitri Nestor Alice Van De Ville, Maria del Carmen Sandi Perez, Maude Schneider, Marie Schaer, Daniela Maria Zöller, Maëlle Chambaz

Background 22q11.2 Deletion Syndrome (22q11DS) confers strongly increased genetic risk for multiple psychiatric disorders. Similarly to the general population, rates of psychiatric comorbidity suggest that common disease mechanisms are shared across dimens ...

2019

Long-term verbal memory deficit and associated hippocampal alterations in 22q11.2 deletion syndrome

Maude Schneider

Chromosome 22q11.2 deletion syndrome (22q11.2DS) is a genetic disease associated with an increased risk for schizophrenia and a specific cognitive profile. In this paper, we challenge the current view of spared verbal memory in 22q11.2DS by investigating v ...

2019

Influence of Minor Cr-Additions to the Growth of Columnar Dendrites in Al-Zn Alloys: Influence of Icosahedral Short Range Order in the Liquid

Michel Rappaz, Güven Kurtuldu

The effect of minute Cr additions on dendritic growth directions in Al-20 wt pct Zn alloy has been investigated. As first evidenced by Gonzales and Rappaz (Metall Mater Trans A 37:2797-2806, 2006) Al-Zn alloys exhibit a Dendrite Orientation Transition (DOT ...

SPRINGER2019

Neural Circuits for Goal-Directed Sensorimotor Transformations

Carl Petersen, Sylvain Crochet, Seung-Hee Lee

Precisely wired neuronal circuits process sensory information in a learning- and context-dependent manner in order to govern behavior. Simple sensory decision-making tasks in rodents are now beginning to reveal the contributions of distinct cell types and ...

ELSEVIER SCIENCE LONDON2019

(Un)crowding modulates recurrent connectivity in the visual cortex

Michael Herzog, Vitaly Chicherov, Maya Anna Jastrzebowska

Introduction: In crowding, neighboring elements impede the perception of a target. Surprisingly, increasing the number of neighboring elements can decrease crowding, i.e., lead to uncrowding (Manassi et al., 2015). Few neuroimaging studies have explored th ...

2019

From adult dentate gyrus neurogenesis to pattern separation

Olivia Gozel

For a few decades, adult dentate gyrus neurogenesis has been widely recognized by the neuroscience community as an intriguing phenomenon. Two observations are particularly puzzling. At the cellular level, the switch from excitation to inhibition of the GAB ...

EPFL2019

Brain Dynamics: Global Pulse and Brain State Switching

Dimitri Nestor Alice Van De Ville

A major challenge in systems-level neuroscience is to understand the dynamic formation and succession of brain states. A new study has extracted reproducible brain states from mouse resting-state fMRI data, revealing interactions between occurrences of the ...

CELL PRESS2019

Redox dysregulation as a link between childhood trauma and psychopathological and neurocognitive profile in patients with early psychosis

Alessandra Griffa, Patric Hagmann, Kim Do

Exposure to childhood trauma (CT) increases the risk for psychosis and affects the development of brain structures, possibly through oxidative stress. As oxidative stress is also linked to psychosis, it may interact with CT, leading to a more severe clinic ...

National Academy of Sciences2018

The physiological variability of channel density in hippocampal CA1 pyramidal cells and interneurons explored using a unified data-driven modeling workflow

Henry Markram, Felix Schürmann, Eilif Benjamin Muller, Werner Alfons Hilda Van Geit, Ying Shi, Jean-Denis Georges Emile Courcol, Armando Romani, Michele Migliore, Maurizio Ferdinando Pezzoli, Szabolcs Kali, Carmen Alina Lupascu, Christian Andreas Rössert, Olivier Richard Hagens, Rosanna Migliore, Luca Leonardo Bologna, Audrey Mercer, Stefano Maximiliano Antonel

Every neuron is part of a network, exerting its function by transforming multiple spatiotemporal synaptic input patterns into a single spiking output. This function is specified by the particular shape and passive electrical properties of the neuronal memb ...

PUBLIC LIBRARY SCIENCE2018

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