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Background and Purpose: Transgenic mice over-expressing Notch2 in the uvea exhibit a hyperplastic ciliary body leading to increased IOP and glaucoma. The aim of this study was to investigate the possible presence of NOTCH2 variants in patients with primary ...
The ciliary body and iris are pigmented epithelial structures in the anterior eye segment that function to maintain correct intra-ocular pressure and regulate exposure of the internal eye structures to light, respectively. The cellular and molecular factor ...
PURPOSE: To determine and compare the origin of the external surface reflections produced by commonly used intraocular lenses (IOLs). METHODS: The specular reflection taking place at the anterior surface of eight types of IOLs (IOL power = 22.00 diopters M ...
Glaucoma is one of the leading causes of blindness in the world. It results in an increase of the aqueous humour (AH) outflow pathway which leads to an increase of the intraocular pressure (IOP). Many treatments exists to reduce and stabilize the IOP such ...
A new holographic technique combining digital holographic microscopy with the use of low coherence light has been developed and the potential of the resulting method for vision in turbid media and biomedical imaging has been evaluated. In digital holograph ...
The eye structure and function highly depend on the stability of the intraocular pressure (IOP). Glaucoma is an ophthalmic disease that can potentially lead to irreversible blindness. Glaucoma results from optic nerve damages due to persistent elevated IOP ...
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We present a high speed full range spectral domain optical coherence tomography system. By inserting a phase modulator into the reference arm and recording of every other spectrum with a 90° phase shift (introduced by the phase modulator) we are able to di ...
Cellular signaling mediated by Notch receptors results in coordinated regulation of cell growth, survival and differentiation. In melanocytes, Notch signaling is essential for the maintenance of melanocytes and the melanocyte stem cell population. Whereas, ...
We show that digital holography can be combined easily with optical coherence tomography approach. Varying the reference path length is the means used to acquire a series of holograms at different depths, providing after reconstruction images of slices at ...