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Transcription factor binding site(s) (TFBS) gain and loss (i.e., turnover) is a well-documented feature of cis-regulatory module (CRM) evolution, yet little attention has been paid to the evolutionary force(s) driving this turnover process. The predominant ...
Alternative splicing, an unknown mechanism 20 years ago, is now recognized as a major mechanism for proteome and transcriptome diversity, particularly in mammals - some researchers conjecture that up to 90% of human genes are alternatively spliced. Despite ...
In this work, we study in detail the sensing characteristics of piezoresistive force sensors based on structured LTCC (Low Temperature Co-fired Ceramic) cantilevers carrying a thick-film piezoresistive bridge. These devices show much improved sensitivity c ...
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The solid oxide fuel cell (SOFC) is a direct energy conversion device, which allows the production of electricity with high efficiency while maintaining pollutant emissions at a low level. It offers better fuel flexibility and lower vulnerability to impuri ...
"There is more virus in us than us in us". John Coffin's famous sentence illustrates that particular nucleic acid sequences related to exogenous viruses, called retrotransposons, constitute almost half of the human genome and largely exceeds the amount of ...
Alternative splicing, an unknown mechanism 20 years ago, is now recognized as a major mechanism for proteome and transcriptome diversity, particularly in mammals-some researchers conjecture that up to 90% of human genes are alternatively spliced. Despite m ...
The emergence of Vertebrata was accompanied by two rounds of whole-genome duplications. This enabled paralogous genes to acquire novel functions with high evolutionary potential, a process suggested to occur mostly by changes in gene regulation, rather tha ...
In this work, we study in detail the sensing characteristics of piezoresistive force sensors based on structured LTCC (Low Temperature Co-fired Ceramic) cantilevers carrying a thick-film piezoresistive bridge. These devices show much improved sensitivity c ...
The immense diversity of microbial life found in the vadose zone reflects the extremely heterogeneous and highly dynamic aquatic and chemical environments formed within soil pore spaces. The notion of planktonian free swimming microbes is unrealistic under ...
We investigate the dynamical features of the adsorption of diphenylalanine molecules on the Cu(I 10) surface and of their assembling into supramolecular structures by a combination of quantum and classical atomistic modeling with dynamic scanning tunneling ...