Concept

Trachea

Related publications (19)

Optimization of a dynamic compression bioreactor to evaluate mechano-transduction in 3D hydrogel-encapsulated cartilage progenitor cells.

Mechanical stimuli have fundamental repercussions on a cell’s phenotype and response in vivo. Studying these effects in a controlled in vitro bioreactor system allows bioengineers to hone in on the regenerative potential of therapeutic cells to better desi ...

2012

Numerical Fluid-Structure Interaction Model for the Connection of Outflow Cannula of LVAD to the Aorta

Alfio Quarteroni, Simone Deparis, Jean Bonnemain, Ludwig Von Segesser

Purpose: Connecting outflow cannula of LVAD to the aorta is an underexplored issue but may have considerable impact. In fact the hemodynamic modifications due to implantation in this region can cause thromboembolic events. It is therefore important to unde ...

2011

Rostral and caudal pharyngeal arches share a common neural crest ground pattern

Denis Duboule

In vertebrates, face and throat structures, such as jaw, hyoid and thyroid cartilages develop from a rostrocaudal metameric series of pharyngeal arches, colonized by cranial neural crest cells (NCCs). Colinear Hox gene expression patterns underlie arch spe ...

2009

Effects of dynamic compression on lentiviral transduction in an in vitro airway wall model

Melody Swartz, Alice Anna Tomei

Asthmatic patients are more susceptible to viral infection, and we asked whether dynamic strain on the airway wall (such as that associated with bronchoconstriction) would influence the rate of viral infection of the epithelial and subepithelial cells. To ...

2008

Effect of elastin degradation on carotid wall mechanics as assessed by a constituent-based biomechanical model

Nikolaos Stergiopoulos, Sylvain Roy, Luca Augsburger, Edouard Fonck, Gilles Prod'Hom

Arteries display a nonlinear anisotropic behavior dictated by the elastic properties and structural arrangement of its main constituents, elastin, collagen, and vascular smooth muscle. Elastin provides for structural integrity and for the compliance of the ...

2007

Nuclear factor of activated T (NFAT) cells activity within CD4+ T cells is influenced by activation status and tissue localisation

Nicola Harris, Benjamin John Marsland

Nuclear factor of activated T (NFAT) cells is a family of transcription factors important for the regulation of cytokine expression by CD4+ T cells. Whilst a number of studies have examined NFAT activity of in vitro generated CD4+ T helper (Th)1 and Th2 ce ...

2006

The functions of mucosal T cells in containing the indigenous commensal flora of the intestine

Nicola Harris, Andrew J. Macpherson

There is an immense load of non-pathogenic commensal bacteria in the distal small intestine and the colon of mammals. The physical barrier that prevents penetration (translocation) of these organisms into the body is a simple epithelium comprised of the si ...

2002

Pharmacokinetics and pharmacodynamics of tetra(m-hydroxyphenyl)chlorin in the hamster cheek pouch tumor model: comparison with clinical measurements

Hubert van den Bergh, Georges Wagnières, Alain Woodtli

The pharmacokinetics (PK) of the photosensitizer tetra(m-hydroxyphenyl)chlorin (mTHPC) was measured by optical fiber-based light-induced fluorescence spectroscopy (LIFS) in the normal and tumoral cheek pouch mucosa of 29 Golden Syrian hamsters with chem. i ...

Elsevier2000

Photodetection and photodynamic therapy of "early" squamous cell carcinomas of the pharynx, oesophagus and tracheo-bronchial tree

Hubert van den Bergh, Christian Depeursinge, Georges Wagnières, André Châtelain

The efficacy of photodynamic therapy (PDT) alone was evaluated on 41 ‘early’ squamous cell carcinomas of the pharynx (10), oesophagus (15) and tracheo-bronchial tree (16). All lesions but two were synchronous second primaries in ENT-patients suffering from ...

1990

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