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First Advanced Bilayer Scaffolds for Tailored Skin Tissue Engineering Produced via Electrospinning and Melt Electrowriting

In vitro skin models are validated methods for screening cosmetics and pharmaceuticals, but still have limitations. The bilayer poly(epsilon-caprolactone) scaffold/membrane model described here overcomes some of these deficits by integrating a solution ele ...

Weinheim2024

Liquid Metal-Based Sensor Skin Enabling Haptic Perception of Softness

Stéphanie Lacour, Ivan Furfaro, Emilio Fernández Lavado, Haotian Chen

Haptic perception of softness is a unique feature of the human skin that relies on the concurrent measurements of the lateral deformation and compression of the skin during object manipulation. This is challenging to implement in robotics because of combin ...

2023

Laser-induced liquid micro-jets for drug delivery

Jan Krizek

Jet injection devices have been studied and developed for transdermal drug delivery to avoid the use of needles. Such contact-less devices provide several advantages such as better dose control, lateral and depth localisation, lower collateral damage than ...

EPFL2021

Oriented MFI membranes by gel-less secondary growth of sub-100 nm MFI-nanosheet seed layers

Kumar Varoon Agrawal, Han Zhang

A zeolite membrane fabrication process combining 2D-zeolite nanosheet seeding and gel-free secondary growth is described. This process produces selective molecular sieve films that are as thin as 100 nm and exhibit record high permeances for xylene- and bu ...

2015

Study of Antimicrobial Peptide Dendrimers on Wound healing in SKin Tissue Engineering

Philippe Abdel Sayed, Ariane Kaeppeli

Infections are one of the most common complications in burn injuries. In severe burns, the wound surface is optimal for microbial proliferation as the exudate is a protein rich environment. Autograft and cultured grafts are the main treatments used nowaday ...

2015

The Nano-Scale Mechanical Properties of the Extracellular Matrix Regulate Dermal Fibroblast Function

Jean-Jacques Meister, Boris Hinz, Lara Buscemi Estefanell, Josiane Angèle Charlotte Smith-Clerc

Changes in the mechanical properties of dermis occur during skin aging or tissue remodeling and affect the activity of resident fibroblasts. With the aim to establish elastic culture substrates that reproduce the variable softness of dermis, we determined ...

Nature Publishing Group2014

Extracellular matrix components in peripheral nerve repair: how to affect neural cellular response and nerve regeneration?

Stéphanie Lacour, Alba Carla De Luca

Peripheral nerve injury is a serious problem affecting significantly patients' life. Autografts are the "gold standard" used to repair the injury gap, however, only 50% of patients fully recover from the trauma. Artificial conduits are a valid alternative ...

Shenyang Editorial Dept Neural Regeneration Res2014

Improving the osteogenic potential of BMP-2 with hyaluronic acid hydrogel modified with integrin-specific fibronectin fragment

Jeffrey Alan Hubbell, Mikaël Martino

While human bone morphogenetic protein-2 (rhBMP-2) is a promising growth factor for bone regeneration, its clinical efficacy has recently shown to be below expectation. In order to improve the clinical translation of rhBMP-2, there exists strong motivation ...

Elsevier2013

The Mechanical Environment Modulates Intracellular Calcium Oscillation Activities of Myofibroblasts

Boris Hinz, Adriano Garonna, Lysianne Follonier Castella

Myofibroblast contraction is fundamental in the excessive tissue remodeling that is characteristic of fibrotic tissue contractures. Tissue remodeling during development of fibrosis leads to gradually increasing stiffness of the extracellular matrix. We pro ...

Public Library Science2013

Fibronectin Binding Modulates CXCL11 Activity and Facilitates Wound Healing

Marco Pisano, Jeffrey Alan Hubbell, Mikaël Martino, Priscilla Suhasna Maithili Briquez, Federico Tortelli

Engineered biomatrices offer the potential to recapitulate the regenerative microenvironment, with important implications in tissue repair. In this context, investigation of the molecular interactions occurring between growth factors, cytokines and extrace ...

Public Library of Science2013

Scar

Liquid Metal-Based Sensor Skin Enabling Haptic Perception of Softness

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First Advanced Bilayer Scaffolds for Tailored Skin Tissue Engineering Produced via Electrospinning and Melt Electrowriting

Liquid Metal-Based Sensor Skin Enabling Haptic Perception of Softness

Laser-induced liquid micro-jets for drug delivery

Oriented MFI membranes by gel-less secondary growth of sub-100 nm MFI-nanosheet seed layers

Study of Antimicrobial Peptide Dendrimers on Wound healing in SKin Tissue Engineering

The Nano-Scale Mechanical Properties of the Extracellular Matrix Regulate Dermal Fibroblast Function

Extracellular matrix components in peripheral nerve repair: how to affect neural cellular response and nerve regeneration?

Improving the osteogenic potential of BMP-2 with hyaluronic acid hydrogel modified with integrin-specific fibronectin fragment

The Mechanical Environment Modulates Intracellular Calcium Oscillation Activities of Myofibroblasts

Fibronectin Binding Modulates CXCL11 Activity and Facilitates Wound Healing

Study of Antimicrobial Peptide Dendrimers on Wound healing in SKin Tissue Engineering

Laser-induced liquid micro-jets for drug delivery

Fibronectin Binding Modulates CXCL11 Activity and Facilitates Wound Healing

The Mechanical Environment Modulates Intracellular Calcium Oscillation Activities of Myofibroblasts

The Nano-Scale Mechanical Properties of the Extracellular Matrix Regulate Dermal Fibroblast Function

Oriented MFI membranes by gel-less secondary growth of sub-100 nm MFI-nanosheet seed layers

Improving the osteogenic potential of BMP-2 with hyaluronic acid hydrogel modified with integrin-specific fibronectin fragment

Extracellular matrix components in peripheral nerve repair: how to affect neural cellular response and nerve regeneration?

First Advanced Bilayer Scaffolds for Tailored Skin Tissue Engineering Produced via Electrospinning and Melt Electrowriting