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Explores DNA replication mechanisms, including speed, errors, proofreading, and semiconservative nature, emphasizing the importance of maintaining DNA fidelity through mismatch repair.
Delves into neuroepigenetics, covering chromatin structure, histone modifications, DNA methylation, and their impact on gene transcription and inheritance.
Explores replicative immortality in cancer cells, focusing on telomere erosion, telomerase activity, and the role of p53 in maintaining genomic stability.
Explores the applications of CRISPR-Cas in genome editing, focusing on engineering bacterial genomes, curing genetic diseases, guide RNA simplicity, Cas9 specificity, DNA damage mechanisms, and base editing.