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Explores the selection and rationale behind preclinical animal models in drug discovery, emphasizing understanding mechanisms of action and domain specificity.
Explores molecular glues as new drug modalities, focusing on binding forces, energetics, biomolecular interactions, quantification, drug development, and structural characterization.
Explores Alzheimer's disease, anxiety, pain, and the renin-angiotensin system, including the development of the first renin inhibitor for clinical treatment.
