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Related lectures (29)

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Therapeutic Monitoring: Tato for Jane Doe

Discusses therapeutic monitoring principles using Bayes' theorem for personalized treatment.

Pharmacodynamics: Ligand-Receptor Interactions and Drug Effects

Explores ligand-receptor interactions, drug effects, modulation mechanisms, and factors influencing drug responses.

Pharmacodynamics: Ligand-Receptor Binding and Drug Effects

Explores ligand-receptor binding, drug effects, efficacy, potency, and biased agonism in pharmacodynamics.

SEGREGATION of KINETIC REACTIVITY & BINDING AFFINITY

The paper focuses on the importance of reversible interactions to potency and mechanisms of drug resistance.

Enzyme Inhibition Mechanisms

Covers enzyme inhibition mechanisms, drug modes of action, targeted protein degradation using PROTACs, and the bump-hole method for protein-ligand engineering.

Pharmacokinetic & Pharmacodynamic Evaluations

Covers the principles of pharmacokinetics and pharmacodynamics, including drug exposure-response relationships.

Machine Learning-Guided Treatment Discovery

Explores personalized medicine, machine learning for treatment prediction, and challenges in traditional algorithms.

Neurotransmitters: Receptors and Effects

Explores major neurotransmitters, their effects, drug therapy, and receptor mechanisms in brain function.

Pharmacokinetics Modeling: Zero and First-Order Kinetics

Explores pharmacokinetics modeling, covering zero and first-order kinetics, drug distribution, and key parameters for drug elimination.

Pharmacokinetic & Pharmacodynamic Studies

Discusses the importance of assessing PK/PD relationships in drug development and the use of multiple PD biomarkers.