Chaperones Effects: Amyloid Beta Peptide Aggregation

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Chaperone-Mediated Disaggregation: Amyloid Fibrils and Hsp70

Explores chaperone-mediated disaggregation of amyloid fibrils by Hsp70 in neurodegenerative diseases.

Understanding Tau Pathologies

Explores Tau pathologies in Alzheimer's and related disorders, covering hyperphosphorylation, propagation, genetic associations, and therapeutic interventions.

Protein Aggregation and Disaggregation: Insights from In Vivo Studies

Explores protein aggregation and disaggregation mechanisms, focusing on huntingtin protein in Huntington's Disease.

Cryo-EM and Parkinson's Disease

Delves into Cryo-EM's role in studying Parkinson's Disease and protein structures at the nano-level.

Multifactorial Diseases

Explores genetic mutations in multifactorial diseases like Alzheimer's and Parkinson's.

The Molecular Interactions that Shape Tau Polymorphs

Explores the molecular interactions shaping tau polymorphs and the role of Hsp40s in regulating tau aggregation.

Polymer Structure and Biological Relevance

Covers the molecular structure of polymers, the transcription process, and the implications of protein misfolding in diseases.

Protein Aggregation Kinetics and Drug Discovery

Explores protein aggregation kinetics, drug discovery, and targeting oligomers in misfolding diseases.

Protein Structure and Function: Folding and Degradation

Covers protein folding, maturation, degradation, and the implications of misfolding in neurodegenerative diseases.

Nucleation and Growth: Interfacial Phenomena

Explores nucleation, growth, Ostwald ripening, LaPlace pressure, Kelvin equation, phase equilibrium, size dependence of phase transitions, critical micelle concentration, self-assembly, temperature dependence of nucleation rate, heterogeneous nucleation, and melting point depression.