Fragment-Based Drug Discovery: Concepts & Technologies

About
Privacy
Disclaimer

Graph Chatbot

Related lectures (32)

Page 3 of 4

Explores cyclic peptides and macrocycles, their applications in drug development, and the role of bicyclic peptides in targeting specific proteins.

Tissue Engineering for Cancer Research

Explores the complexity of cancer, challenges in research translation, and the applications of tissue engineering for cancer models and drug screening.

Identifying Correct Target in Medical Chemistry

Explores target identification, efficacy, and safety in medical chemistry, emphasizing the importance of on-target specificity and drug design.

Protein-Ligand Interactions

Explores the principles of protein-ligand interactions, covering methods for measuring affinity and kinetics in drug development.

Selective Drug Targeting Mechanisms

Explores selective drug targeting mechanisms, resistance development, tuberculosis incidence, BCR-ABL mutations, tyrosine kinase inhibitors, drug toxicity, interactions, and toxicology studies.

Preclinical Animal Models: Selection & Rationale

Explores the selection and rationale of preclinical animal models in drug development, emphasizing the 10 to 15-year path to a marketed small-molecule drug.

RNA-based Approaches to Disease Treatment

Explores RNA-based disease treatment, synthetic biology impact on therapeutics, and programmable RNA-targeting tools.

Introduction: small molecule drugs for cancer

Introduces small molecule drugs for cancer treatment, covering drug discovery, mechanisms of action, and historical development of anti-cancer agents.

Drug-Induced Liver Injury (DILI): Mechanisms and Mitigation

Delves into Drug-Induced Liver Injury (DILI) mechanisms, metabolism, and mitigation strategies in drug development.

Enzyme Drug Targets

Explores enzyme drug targets, tyrosine kinase inhibitors, vascular tone control, and viral life cycle interventions.