Lecture
Receptor Tyrosine Kinases: Signalling and Regulation
In course
DEMO: labore eu occaecat adipisicing
Qui proident nulla in officia in tempor tempor pariatur id consequat sit incididunt non. Adipisicing commodo consequat magna adipisicing aute enim laborum incididunt adipisicing dolore. Enim cillum occaecat fugiat incididunt culpa in et ad laboris excepteur consectetur elit velit nulla.
Description
This lecture covers the structure and function of receptor tyrosine kinases (RTKs), focusing on their activation through ligand binding, dimerization, and phosphorylation. It explores the downstream signalling cascades initiated by RTKs and the regulatory mechanisms involved. The lecture also discusses the implications of RTK dysregulation in diseases such as cancer, highlighting the potential therapeutic strategies targeting RTKs. Additional topics include the auto-inhibition mechanisms and the pharmaceutical approaches for targeting RTKs. Further reading suggestions are provided for a deeper understanding of RTK biology.
Instructor
ipsum in duis anim
Proident cillum consequat dolor proident aute nulla ea officia esse fugiat minim exercitation proident duis. Fugiat sunt incididunt officia esse voluptate. Dolor tempor mollit officia laboris velit consequat duis exercitation. Duis aliqua excepteur eiusmod consequat ex qui adipisicing. Aliqua qui duis non voluptate aute.
Official source
About this result
This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.
Ontological neighbourhood
Related lectures (47)
Cell Signalling: Receptors and Pathways
Explores cell signalling mechanisms, including receptors, pathways, and signal transduction for gene regulation and cellular responses.
Cellular Communication: Signaling Pathways and Receptors
Delves into the importance of intercellular communication and the diverse signaling pathways involved in cellular responses.
Protein Phosphorylation: Mechanisms & Regulation
Explores protein phosphorylation, detailing common modifications like acetylation and ubiquitination, kinase specificity, and activation mechanisms.
Protein Phosphorylation: Mechanisms and Regulation
Explores protein phosphorylation, its structural effects, kinase activity, and its role in signaling and disease.
Post-translational Modifications of Proteins
Provides an overview of protein post-translational modifications, including phosphorylation, ubiquitination, and acylation.