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This lecture covers the processes of glycolysis and gluconeogenesis, focusing on the regulation of glucose metabolism at the cellular and organism levels. It explains the reciprocal regulation of these pathways, the role of enzymes like hexokinase and phosphofructokinase-1, and the significance of hormones like insulin and glucagon. Additionally, it delves into glycogen metabolism, detailing glycogen synthesis, breakdown, and the branching enzyme's role. The lecture also discusses the activation of glucose molecules, the formation of glycogen primers, and the elongation of glycogen chains. Lastly, it explores the regulation of glycogen metabolism through enzymes like glycogen phosphorylase and glycogen synthase, highlighting the interplay between insulin, glucagon, and other factors.