Molecular Mechanism of Chaperonin GroEL

About
Privacy
Disclaimer

Graph Chatbot

Related lectures (31)

Page 2 of 4

Explores protein structures, folding principles, and sequence determinants, emphasizing the diverse three-dimensional structures proteins can adopt.

Chaperone-Mediated Disaggregation: Amyloid Fibrils and Hsp70

Explores chaperone-mediated disaggregation of amyloid fibrils by Hsp70 in neurodegenerative diseases.

Cellular Heat Shock Response: Rethinking the Significance

Delves into the cellular heat shock response, emphasizing the absence of a sensor mechanism and the restoration of misfolded protein aggregates.

Hsp70 Mechanism: Unfolding & Entropic Pulling

Explores Hsp70's role in protein unfolding and entropic pulling, discussing chaperone-driven stabilization and ATP hydrolysis.

Protein Folding: Navigating Energy Landscapes

Explores protein folding, chaperone assistance, entropy impact, and non-equilibrium states in protein stabilization.

Mitochondrial Dynamics: Hsp70 and MBP Folding

Delves into mitochondrial Hsp70 and MBP folding dynamics from a single molecule perspective.

Hsp70 Chaperone Binding: Substrate Selectivity and Function

Explores the selective promiscuity in binding of the E. coli Hsp70 chaperone to unfolded or misfolded protein substrates, examining its implications in protein folding mechanisms.

Protein Structure and Function: Folding and Degradation

Covers protein folding, maturation, degradation, and the implications of misfolding in neurodegenerative diseases.

Post-translational regulation of ER proteostasis

Explores the post-translational regulation of ER proteostasis, focusing on BiP chaperone activity, ER stress response, and FICD-mediated AMPylation.

Protein Structure & Modifications

Explores protein structure analysis, folding, modifications, and their impact on diseases and protein activity regulation.