Bioprocess Sterilization

This lecture covers the principles and methods of bioprocess sterilization, including thermal, chemical, and irradiation techniques. It discusses the importance of heat inactivation of microorganisms, the concept of D-value, z-value, and F-value, and the kinetics of heat sterilization. The instructor emphasizes the significance of sterilization in maintaining sterility and safety in bioprocesses, as well as the critical quality attributes (CQAs) and process parameters involved in the sterilization process.